Now showing items 11-20 of 36
Functional analogs for the reduction of certain nitrogenase substrates. Are multiple sites within the Fe/Mo/S active center involved in the 6e – reduction of N 2 ?
(Springer-Verlag; Society of Biological Inorganic Chemistry, 1996-12)
Reactivity studies of clusters that contain the MFe 3 S 4 cores (M = Mo, V) with catecholate, multicarboxylate (or DMF) ligands coordinated to the Mo (or V) atoms, and Cl ligands coordinated to the Fe atoms have been ...
Discriminative stimulus effects of a centrally administered, delta-opioid peptide (d-Pen2-d-Pen5-enkephalin) in pigeons
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1996-10)
The present study assessed the discriminative stimulus effects of the delta-opioid agonist [ d -Pen 2 - d -Pen 5 ]enkephalin (DPDPE) in pigeons. Food-restricted pigeons were trained to discriminate between ICV injections ...
Treatment of Gaucher disease with an enzyme inhibitor
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-04)
The hypothesis is offered predicting that Caucher patients could be treated with a drug that slows the synthesis of glucosylceramide, the lipid that accumulates in this disorder. The present therapeutic approach involves ...
Membrane adsorption characteristics determine the kinetics of flow-through transductions
(Wiley Subscription Services, Inc., A Wiley Company, 1996-08-05)
Retrovirus-mediated gene transfer is currently limited by random Brownian motion of the retrovirus. This limitation can be overcome by flowing the retrovirus solution through a porous membrane that supports the target ...
Structural requirements for binding to the δ opioid receptor: Alkyl replacements at the third residue of deltorphin I
(Kluwer Academic Publishers; ESCOM Science Publishers B.V. ; Springer Science+Business Media, 1996-01)
The naturally occurring heptapeptide deltorphin I (Tyr- d -Ala-Phe-Asp-Val-Val-Gly-NH 2 ) exhibits extremely high affinity and selectivity for the δ opioid receptor. In an ongoing investigation of the features of this ...
Characterization of gangliosides from Ehrlich ascites tumour cells and their variants
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-04)
Differences in the nature of the gangliosides present in two types of Ehrlich ascites tumour (EAT) cells, the adherent and non-adherent EAT cells, were studied. Gangliosides were isolated by DEAE Sephadex column chromatography ...
Molecular Cloning of Two Different Mannose-Binding Lectins from Tulip Bulbs
(Blackwell Science Ltd, 1996-03)
The peptidolytic capacity of the spirochete system
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1996-06)
Relatively scant chemical information has been available on the proteinases and peptidases of spirochetes in spite of the association of spirochetes with several serious infections known to plague humans and other animal ...
Unilineage model of hematopoiesis predicts self-renewal of stem and progenitor cells based on ex vivo growth data
(Wiley Subscription Services, Inc., A Wiley Company, 1996-10-05)
Stem cell models are used to describe the function of several tissues. We present unilineage kinetic description of stem cell models and their application to the analysis of ex vivo hematopoietic cell expansion data. This ...
Successful and unsuccessful approaches to imaging carcinoids: Comparison of a radiolabelled tryptophan hydroxylase inhibitor with a tracer of biogenic amine uptake and storage, and a somatostatin analogue
(Springer-Verlag, 1996-02)
A mouse mastocytoma model was used to determine the biodistribution and tumour uptake of four radiopharmaceuticals developed to target the serotonin synthetic pathway in carcinoid tumours. Three of the compounds were ...