Now showing items 31-40 of 44
Surface-modified poly(lactide- co -glycolide) nanospheres for targeted bone imaging with enhanced labeling and delivery of radioisotope
(Wiley Subscription Services, Inc., A Wiley Company, 2003-12-01)
Surface-modified nanospheres can be utilized for targeting drugs and diagnostic agents to the bone and bone marrow while extending their circulation time in the blood stream. The surface modification of poly(lactide- co ...
Cementum engineering with three-dimensional polymer scaffolds
(Wiley Subscription Services, Inc., A Wiley Company, 2003-10-01)
Cloned cementoblasts (OCCMs), periodontal ligament fibroblasts (SV-PDLs), and dental follicle (SV-F) cells obtained from mice were used as a tool to study periodontal tissue engineering. OCCM, SV-PDL, and SV-F cells were ...
Alginate type and RGD density control myoblast phenotype
(Wiley Subscription Services, Inc., A Wiley Company, 2002-05)
Alginates are being increasingly used for cell encapsulation and tissue engineering applications; however, these materials cannot specifically interact with mammalian cells. We have covalently modified alginates of varying ...
Measuring the Electrical Stapedius Reflex with Stapedius Muscle Electromyogram Recordings
(Kluwer Academic Publishers-Plenum Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 2002-02)
Previous studies have demonstrated a correlation between cochlear implant recipients' comfort levels ( C level, upper limit of dynamic range of stimulation) and the contralateral electrical stapedius reflex (ESR) threshold, ...
A Theoretical Model of a Molecular-Motor-Powered Pump
(Kluwer Academic Publishers; Springer Science + Business Media, Inc., 2005-03)
The motion of a cylindrical bead in a fluid contained within a two-dimensional channel is investigated using the boundary element method as a model of a biomolecular-motor-powered microfluidics pump. The novelty of the ...
Disruption of Endosomal Membrane by Cationic Vectors Drives Endosomal Release and Enables Successful Gene Delivery
(2016)
The potential of gene therapy to treat congenital disorders is hindered by the lack of safe and effective delivery agents (vectors). More effective viral vectors possess several safety concerns but the safer non-viral ...
Targeting Branched Chain Amino Acid Metabolism in Tumor Microenvironment
(2020)
Branched Chain amino acids (BCAAs) play an essential role in cell metabolism supplying both carbon and nitrogen in pancreatic cancers, and their increased levels have been associated with increased risk of pancreatic ductal ...
Ultrafast Microfluidic Immunoassays Towards Real-time Intervention of Cytokine Storms
(2020)
Biomarker-guided precision medicine holds great promise to provide personalized therapy with a good understanding of the molecular or cellular data of an individual patient. However, implementing this approach in critical ...
Exploring the Function of Polyphosphate in the Contact Pathway of Blood Clotting and Developing Polyphosphate Probes for Enhanced Specificity
(2021)
The classic coagulation cascade has been well-studied for many years. In the traditional “waterfall” model, both the contact pathway and the tissue factor pathway can trigger blood clotting. The contact pathway is composed ...
The Role of Collagen Cross-linking in Craniofacial and Long Bone Mineralization and Healing
(2021)
Compromised collagen and mineral can lead to decreases in bone quantity and quality in a variety of diseases that differentially affect craniofacial and long bones. Since bone is a composite - with mineral lending stiffness ...