Now showing items 91-96 of 96
Direct Identification and Counting of MicroRNAs in Single Cells by Transient Binding and Kinetic Fingerprinting
(2023)
Cancer is the second leading cause of mortality worldwide. Within the U.S. alone, it is estimated that 1.9 million people will be diagnosed this year and over 610,000 people are expected to perish. Despite advances in ...
Development and Application of Numerical Methods in Biomolecular Solvation
(2021)
This work addresses the development of fast summation methods for long range particle interactions and their application to problems in biomolecular solvation, which describes the interaction of proteins or other biomolecules ...
Interactions Between Fluorescent Molecules and Plasmonic Nanoparticles: A Super-Resolution Study
(2017)
Single-molecule super-resolution imaging techniques play an increasingly important role in studying complex fine structures, dynamics and interactions in nanoscale confined spaces. The resolution of this technique can be ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Molecular Dynamics Simulation of Phase and Structural Transitions in Model Lung Surfactant Mixtures.
(2010)
Lung surfactant (LS) is a complex mixture of lipids and proteins that reduces and regulates the surface tension in the lungs, thereby decreasing the work of breathing. A thorough understanding of LS function is critical ...
Solid State NMR Investigations of Lipid Bilayers and Biomembrane Binding Molecules: Dendrimers and Amylin.
(2010)
The goal of this project was to investigate the interaction between lipid binding molecules, such as peptides and drug compounds, with biological lipid bilayers. The results demonstrate that human amylin, a peptide hormone ...