Now showing items 3171-3180 of 3194
Systematic Improvement of Quantification and Formulation of Synthetic Protein Nanoparticles for Gene Delivery
(2022)
Gene therapy is a promising field for the generation of new and more effective therapies, but its application is stymied by the lack of safe and efficient delivery vehicles. Furthermore, gene delivery system optimization ...
Stochastic Modeling of the Formation of Aromatics in Combustion
(2021)
Understanding the formation of polycyclic aromatic compounds (PACs) in combustion not only bridges the knowledge gap between the small gas-phase species and incipient soot particles, but may also help address the global ...
Polymer Nanoparticle Design for Ovarian Cancer Therapies
(2021)
Ovarian cancer is the fifth leading cause of cancer related death in females and current clinical treatments have low patient survival rates. Nanoparticle drug delivery has been promoted as an effective therapy, however ...
Utilization of Nanoparticles for Photoacoustic Chemical Imaging
(2018)
Tumors are known to have unique chemical properties, such as low pH (acidosis), high K+ (hyperkalemia), and low O2 (hypoxia). Tumor acidosis has been known to influence therapeutic activities of chemotherapeutic drugs. ...
Theoretical and Experimental Study of Fuel Injector Tip Wetting as a Source of Particulate Emissions in Gasoline Direct-Injection Engines
(2019)
Gasoline fuel film deposited on the tip of a fuel injector, i.e. injector tip wetting, has been identified as a significant source of particulate emissions at some operating conditions of gasoline direct-injection engines. ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Molecular Dynamics Simulation of Phase and Structural Transitions in Model Lung Surfactant Mixtures.
(2010)
Lung surfactant (LS) is a complex mixture of lipids and proteins that reduces and regulates the surface tension in the lungs, thereby decreasing the work of breathing. A thorough understanding of LS function is critical ...
White-Light Generation and OLED Lifetime Issues.
(2008)
This thesis presents experimental results and discussion regarding issues related to organic light-emitting devices (OLEDs). In particular, this thesis has three main focuses: the generation of white light from Förster ...
Optical and Magnetic Manipulation of Hybrid Micro and Nanoparticle Sensors.
(2008)
Microparticles and nanoparticles have been used in a wide variety of applications ranging from biomedical to optical and electronic technologies. The microscopic and mesoscopic size scale of single particles makes them ...
A Building Block Approach Towards Novel Nonlinear Optical Materials.
(2007)
The purpose of the present research is to develop and apply a building block approach towards the design of novel nonlinear optical materials, capable of exhibiting enhanced Two-Photon Absorption (TPA) behavior. These ...