Now showing items 51-60 of 100
Classifications of ovarian cancer tissues by proteomic patterns
(WILEY-VCH Verlag, 2006-11)
Ovarian cancer is a morphologically and biologically heterogeneous disease. The identification of type-specific protein markers for ovarian cancer would provide the basis for more tailored treatments, as well as clues for ...
Improved Electrochemical Analysis of Neuropathy Target Esterase Activity by a Tyrosinase Carbon Paste Electrode Modified by 1-Methoxyphenazine Methosulfate
(Kluwer Academic Publishers; Springer, 2005-08)
A graphite-paste tyrosinase biosensor was improved by adding 1-methoxyphenazine methosulfate as a mediator. Mediator modification enhanced sensitivity to phenol 4-fold and long-term stability 3-fold. Phenol could be detected ...
Molecular characterization of the endoplasmic reticulum: Insights from proteomic studies
(WILEY-VCH Verlag, 2010-11)
The endoplasmic reticulum (ER) is a multifunctional intracellular organelle responsible for the synthesis, processing and trafficking of a wide variety of proteins essential for cell growth and survival. Therefore, ...
The interaction profile of homologous recombination repair proteins RAD51C, RAD51D and XRCC2 as determined by proteomic analysis
(WILEY-VCH Verlag, 2009-08)
The RAD51 family of proteins is involved in homologous recombination (HR) DNA repair and maintaining chromosome integrity. To identify candidates that interact with HR proteins, the mouse RAD51C, RAD51D and XRCC2 proteins ...
Proteomics analysis of rough endoplasmic reticulum in pancreatic beta cells
(Wiley Periodicals, Inc., 2015-05)
Proteomic analysis reveals perturbed energy metabolism and elevated oxidative stress in hearts of rats with inborn low aerobic capacity
(WILEY‐VCH Verlag, 2011-08)
Selection on running capacity has created rat phenotypes of high‐capacity runners (HCRs) that have enhanced cardiac function and low‐capacity runners (LCRs) that exhibit risk factors of metabolic syndrome. We analysed ...
Electrodeless direct current dielectrophoresis using reconfigurable field-shaping oil barriers
(WILEY-VCH Verlag, 2007-12)
We demonstrate dielectrophoretic (DEP) potential wells using pairs of insulating oil menisci to shape the DC electric field. These oil menisci are arranged in a configuration similar to the quadrupolar electrodes, typically ...
Identification of blood‐protein carriers of the CA 19‐9 antigen and characterization of prevalence in pancreatic diseases
(WILEY‐VCH Verlag, 2011-09)
The current best serum marker for pancreatic cancer, CA 19‐9, detects a carbohydrate antigen on multiple protein carriers. Better knowledge of the protein carriers of the CA 19‐9 antigen in various disease states may lead ...
Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2016–2018)
(Wiley Periodicals, Inc., 2019-01)
One of the most cited limitations of capillary and microchip electrophoresis is the poor sensitivity. This review continues to update this series of biannual reviews, first published in Electrophoresis in 2007, on developments ...
A computational approach to inferring cellular protein-binding affinities from quantitative fluorescence resonance energy transfer imaging
(WILEY-VCH Verlag, 2009-12)
Fluorescence resonance energy transfer (FRET) microscopy can measure the spatial distribution of protein interactions inside live cells. Such experiments give rise to complex data sets with many images of single cells, ...