Now showing items 531-540 of 578
The Effect of Upper Limb Prosthesis Type on Functional Outcomes and Satisfaction
(2019)
Despite the significant functional limitations imposed by upper limb loss, little research has focused on quantifying the functional success and satisfaction of prosthesis users. Most existing evidence comes from surveys, ...
Accelerated Systems for Pattern Matching
(2021)
Pattern matching forms the core of many applications and contributes to a significant fraction of their execution time. For instance, scanning the human reference genome for motifs and identifying variations between ...
Designing System Support for Sharing Everyday Data for Chronic Care
(2022)
The prevalence of chronic conditions has shifted care settings into private homes. In addition, the increasing availability of physical- and algorithmic-sensing solutions promises large quantities of data about one’s ...
Multiscale Modeling of Tuberculosis Disease and Treatment to Optimize Antibiotic Regimens
(2020)
Tuberculosis (TB) is one of the world’s deadliest infectious diseases. Caused by the pathogen Mycobacterium tuberculosis (Mtb), the standard regimen for treating TB consists of treatment with multiple antibiotics for at ...
The Role of Collagen Cross-linking in Craniofacial and Long Bone Mineralization and Healing
(2021)
Compromised collagen and mineral can lead to decreases in bone quantity and quality in a variety of diseases that differentially affect craniofacial and long bones. Since bone is a composite - with mineral lending stiffness ...
Advances in Quantitative MRI: Acquisition, Estimation, and Application
(2018)
Quantitative magnetic resonance imaging (QMRI) produces images of potential MR biomarkers: measurable tissue properties related to physiological processes that characterize the onset and progression of specific disorders. ...
Development Of An Artificial Membrane Lung
(2016)
End-stage lung disease due to chronic obstructive pulmonary disease (COPD) is a leading cause of death across the world. However, treatment options for end-stage COPD are extremely limited. An artificial membrane lung ...
On the Prediction of Pelvic Floor Muscle Injury during Vaginal Delivery in Nullipara: Anthropometric and Viscoelastic Biomechanical Analyses
(2017)
The goal of this research was to provide clinicians with a new framework for preventing pelvic floor muscle tears during vaginal birth. Currently these tears occur in 15% of first time mothers.
In Chapter 2 we developed ...
Engineering Platforms for Mimicking Cellular Processes using Cell-Free Expression Systems
(2020)
Bottom-up in vitro reconstitution has provided fundamental insights into the mechanisms of key cellular processes. Traditional reconstitution methods rely on protein purification as the primary means of extracting functional ...
Isolation and Analysis of Circulating Tumor Cells in Genitourinary Cancers
(2017)
While accessible by a relatively noninvasive blood draw, circulating tumor cells (CTCs) remain difficult to study because of their rarity and their presence amongst the billions of surrounding normal blood cells. Of ...