Now showing items 571-578 of 578
RF Pulse Design for Parallel Excitation in MRI.
(2008)
Parallel excitation in MRI uses localized coils driven by independent RF waveforms as a mechanism for spatially encoding RF energy deposition.
Because localized coil (or sensitivity) encoding is imposed instantaneously, ...
SMARTS Approach to Chemical Data Mining and Physicochemical Property Prediction.
(2009)
The calculation of physicochemical and biological properties is essential in order to facilitate modern drug discovery. Chemical spaces dimensionalized by these descriptors have been used to scaffold-hop in order to discover ...
Memory, Interference and Depression.
(2010)
This dissertation explores the role of interference in short-term memory and how interference in memory may influence depression. The first chapter tackles whether forgetting in the short-term is due to decay with the ...
Regulating Gene Expression Through DNA Mechanics: Tightly Looped DNA Represses Transcription.
(2010)
It is now widely accepted that the mechanical state of DNA can play a major role in regulating the activity of RNA polymerase (RNAP). Not only have the global levels of supercoiling been shown to regulate transcription, ...
Engineering the Quantitative PCR Assay for Decreased Cost and Complexity.
(2011)
The quantitative polymerase chain reaction (qPCR) is an assay of target nucleic acid concentration. Clinical applications of quantitative PCR include measurement of HIV viral load, measurement of bacterial infection, and ...
Transparent and Self-Healing Elastomers for Reconfigurable 3D Materials
(Wiley Periodicals, Inc., 2022-12)
Transparent soft materials are widely used in applications ranging from packaging to flexible displays, wearable devices, and optical lenses. Nevertheless, soft materials are susceptible to mechanical damage, leading to ...
Engineering Multifunctional Nanoparticles: Applied Nanoscale Therapeutics
(2022)
Decades of research towards the development of nanomedicines have, to date, yielded minimal
clinical impact. Focused particularly on the treatment of cancer, the relatively low
number of pursued technologies to reach the ...
Pre-Clinical Investigation of Histotripsy for Non-Invasive Ablation of Liver Cancer
(2022)
Liver cancer, including hepatocellular carcinoma (HCC) is one of the top ten causes of cancer related deaths worldwide and in the United States. The liver is also a frequent site for metastases originating from colorectal ...