Now showing items 11-20 of 31
Strategies for Optimizing Information Extraction from Cortical Recordings.
(2011)
Penetrating neural probe technologies provide researchers with the capability to stimulate and record chemical and electrical signals in the brain. While present technology has yielded significant insight into the function ...
Technologies for Multiphoton 3D Endomicroscopy using MEMS Scanners
(2021)
There has been growing interest in developing endomicroscopy systems as scientific tools for in-vivo imaging in small animals like mice. A well-designed endomicroscope for in-vivo imaging in mice could be used in assessing ...
Local to Global Multi-Scale Multimedia Modeling of Chemical Fate and Population Exposure
(2017)
To assess environmental and human exposure to chemical emissions, two types of approaches are available: 1. intermediate- to high-resolution, substance/location-specific analyses, and 2. lower resolution, less specific ...
Developing and Applying Microdroplet Co-Cultivation Technology for Elucidating Bacterial Interspecies Interactions in the Human Vaginal Microbiome
(2020)
The role of the human vaginal microbiome (HVM) has gained increased recognition
due to recent technological advancements that helped link community composition
and women's health risks. However, the ecological roles of ...
Design and Testing Novel Wearable Instrumentation for Assessing Pelvic Floor Function and Exploring Continence Mechanisms
(2020)
Urinary incontinence (UI) and fecal incontinence (FI) affect 20% of North Americans, with a higher prevalence in women and the elderly. The prevention and treatment of these conditions unfortunately leaves much to be ...
The Influence of Idiopathic Chronic Neck Pain on Sternocleidomastoid and Upper Trapezius Muscle Activity and Elasticity
(2022)
Approximately half of all adults will experience neck pain. Without early detection and proper treatment, neck pain will likely become chronic. Chronic neck pain is one of the primary causes of disability in the United ...
Capacity-Demand Relationships in One-Legged Balance: Biomechanical Analyses
(2019)
A common screening test of balance is the timed ability to stand on one leg for as long as possible. A balance time of 5 s or less is an indicator that the patient has an elevated risk for fall-related injuries. But why ...
Mechanisms and Engineering of Polymeric Nanoparticles for Modulating Innate and Adaptive Immune Responses
(2019)
The delivery of disease-relevant antigens by nanoparticles is a promising strategy for selectively inhibiting pathogenic autoreactive cells while maintaining a protective immune repertoire. This process, known as ...
Microfluidic Technologies for Bioanalytical Chemistry: Advancing Epigenetic Profiling via Chromatin Immunoprecipitation in Droplets
(2019)
Beyond the linear sequence of the genome, the epigenome dynamically controls chromatin remodeling and transcriptional poise without inducing changes in DNA sequence. These epigenetic mechanisms, particularly modifications ...
Evaluating the Effects of Powered Prostheses on Walking Biomechanics In and Out of the Lab
(2021)
Powered ankle prostheses aim to replicate the biological ankle function for individuals with transtibial amputation. The effects of powered prostheses on gait have been experimentally quantified in several studies. The ...