Now showing items 431-439 of 439
Specialized Metabolites and Related Biosynthetic Enzymes in Tomato Glandular Trichomes: Defining Biological Functions of Specific Gland Types.
(2011)
Trichomes are tiny appendages that grow out from the surfaces of leaves, stems, flowers, and other above-ground parts of many plants. They contribute to important biological functions such as determent of herbivores, ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Regulation of Bone Formation and Pathology by Local Actions of Leptin in the Bone Marrow.
(2011)
Site-specific adipose content of the bone marrow has been noted since the inclusion
of meat into the hominid diet, evidenced by marrow removal from ungulate limb
bones, 2.6 million years ago. Association between marrow fat ...
The Application of Genetic, In Silico and In Vitro Tools to Elucidate the Biology of a Functional Amyloid Fiber.
(2010)
Curli are thin aggregative fimbriae produced by many Enterobacteriaceae as a structural component of biofilms. Curli share many biochemical and biophysical properties with amyloid fibers which are often associated with ...
Directed Evolution Designed to Optimize the in vivo Protein Folding Environment.
(2010)
Protein folding is assisted by molecular chaperones and folding catalysts in vivo. Understanding how chaperones are regulated and how they function in vivo may provide new avenues for developing protein folding modulators. ...
Regulating Gene Expression Through DNA Mechanics: Tightly Looped DNA Represses Transcription.
(2010)
It is now widely accepted that the mechanical state of DNA can play a major role in regulating the activity of RNA polymerase (RNAP). Not only have the global levels of supercoiling been shown to regulate transcription, ...
The Landscape of C. elegans 3'UTRs.
(2011)
The 3’ untranslated regions (3’UTRs) of mRNAs have recently been shown to play major roles in gene regulation by interaction with small (21-26nt length) RNAs, such as microRNAs and small interfering RNAs (siRNAs). Recent ...
Intergenerational arsenic exposure on the mouse epigenome and metabolic physiology
(John Wiley & Sons, Inc., 2023-02)
Inorganic arsenic (iAs) is one of the largest toxic exposures to impact humanity worldwide. Exposure to iAs during pregnancy may disrupt the proper remodeling of the epigenome of F1 developing offspring and potentially ...
Exploring Novel Enzyme Activity and Genetic Diversity Through Biocatalytic Engineering and Microbiome Mapping
(2021)
Nature provides us with a wealth of natural product molecules and biological catalysts that represent a rich source of new life-saving pharmaceutical medicines and biotechnological tools for green chemistry. The synthetic ...