Now showing items 1521-1528 of 1528
Functional Status, Quality of Life, and Long-Term Survival in a Cohort of Women with Breast Cancer and Heart Failure: Results of the Medicare Health Outcomes Survey
(2017)
The aging population and marked growth of chronic non-communicable disease pose new challenges for the United States healthcare system. Breast cancer survivors with complex chronic conditions are a growing population. Of ...
Cognitive Function, Self-care, and Glycemic Control in Rural Adults with Type 2 Diabetes
(2017)
Cognitive Function, Self-Care, and Glycemic Control in Rural Adults with Type 2 Diabetes
Abstract
The prevalence of type 2 diabetes mellitus (DM) has increased dramatically over the past two decades, particularly among ...
Development Of An Artificial Membrane Lung
(2016)
End-stage lung disease due to chronic obstructive pulmonary disease (COPD) is a leading cause of death across the world. However, treatment options for end-stage COPD are extremely limited. An artificial membrane lung ...
The Function of the ASH1L Histone Methyltransferase in Cancer: A Chemical Biology Approach
(2018)
ASH1L (absent, small, or homeotic-like 1) is a histone lysine methyltransferase (KMTase) that is overexpressed in cancer and activates oncogenic HOX genes. Small molecule inhibitors of ASH1L would be invaluable tools to ...
Knee Osteoarthritis: Intersections of Obesity, Inflammation, and Metabolic Dysfunction.
(2012)
Background: Obesity is a risk factor for osteoarthritis (OA) and may impart joint-damaging effects through dysfunctional metabolic mechanisms associated with increased adipose tissue.
Objective: To evaluate the relationship ...
Identifying Optimal Anemia Management Practices in Hemodialysis
(2019)
Optimal anemia management strategies for end-stage kidney disease patients treated with hemodialysis are unknown, with controversies over how best to utilize erythropoiesis-stimulating agents (ESA) and intravenous iron to ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Role of CHD7 in Neural Development and Maintenance.
(2011)
Normal tissue development and maintenance require precise timing and correct localization of gene expression. Several lines of evidence indicate that the chromodomain (CHD) family of proteins are critical regulators of ...