Now showing items 141-150 of 153
Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2012–2014)
(Wiley Periodicals, Inc., 2015-01)
ProTrack: An Interactive Multi‐Omics Data Browser for Proteogenomic Studies
(Wiley Periodicals, Inc., 2020-11)
The Clinical Proteomic Tumor Analysis Consortium (CPTAC) initiative has generated extensive multi‐omics data resources of deep proteogenomic profiles for multiple cancer types. To enable the broader community of biological ...
Comparison of Proteomic Assessment Methods in Multiple Cohort Studies
(Humana PressWiley Periodicals, Inc., 2020-06)
A novel method of high‐purity extracellular vesicle enrichment from microliter‐scale human serum for proteomic analysis
(Endotext, MDText.com, Inc.Wiley Periodicals, Inc., 2021-02)
We have developed a rapid, low‐cost, and simple separation strategy to separate extracellular vesicles (EVs) from a small amount of serum (i.e.,<100 μL) with minimal contamination by serum proteins and lipoprotein particles ...
CE‐MS with electrokinetic supercharging and application to determination of neurotransmitters
(Wiley Periodicals, Inc., 2019-11)
Electrokinetic supercharging (EKS) is known as one of the most effective online electrophoretic preconcentration techniques, though pairing with it with mass spectrometry has presented challenges. Here, EKS is successfully ...
FRACPRED- 2D- PRM: A Fraction Prediction Algorithm- Assisted 2D Liquid Chromatography- Based Parallel Reaction Monitoring- Mass Spectrometry Approach for Measuring Low- Abundance Proteins in Human Plasma
(Wiley Periodicals, Inc., 2020-12)
Multidimensional fractionation- based enrichment methods improve the sensitivity of proteomic analysis for low- abundance proteins. However, a major limitation of conventional multidimensional proteomics is the extensive ...
Dual‐detection approach for a charge variant analysis of monoclonal antibody combination products using imaged capillary isoelectric focusing
(Wiley Periodicals, Inc.Springer Science+Business Media, 2022-09)
The clinical benefits of treatments with a combination of two or more therapeutic monoclonal antibodies (mAbs) have emerged in recent years. Imaged capillary isoelectric focusing is a frequently used technology in the ...
Biological Applications of Surfaces with Extreme Wettabilities
(2019)
Surfaces with extreme wettabilities have become an increasingly popular topic due to their wide range of applications – from simply keeping dirt off clothing to oil-water separation in the event of an oil spill. In particular, ...
PSM Small Peptide Toxins Form Functional Bacterial Amyloids in the Staphylococcus aureus Biofilm Matrix.
(2014)
Staphylococcus aureus is a Gram-positive opportunistic pathogen colonizing mammalian hosts. Like many bacteria, S. aureus forms multicellular aggregates called biofilms. Biofilms are surface-associated communities of ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...