Now showing items 2581-2590 of 2593
Hybrid U-Net-based deep learning model for volume segmentation of lung nodules in CT images
(SpringerWiley Periodicals, Inc., 2022-11)
ObjectiveAccurate segmentation of the lung nodule in computed tomography images is a critical component of a computer-assisted lung cancer detection/diagnosis system. However, lung nodule segmentation is a challenging task ...
Ascertainment of vaccination status by self-report versus source documentation: Impact on measuring COVID-19 vaccine effectiveness
(Wiley Periodicals, Inc.Centers for Disease Control and Prevention, 2022-11)
BackgroundDuring the COVID-19 pandemic, self-reported COVID-19 vaccination might facilitate rapid evaluations of vaccine effectiveness (VE) when source documentation (e.g., immunization information systems [IIS]) is not ...
Time to dementia diagnosis by race: A retrospective cohort study
(John Wiley & Sons, Inc., 2022-11)
BackgroundNon-Hispanic Black individuals may be less likely to receive a diagnosis of dementia compared to non-Hispanic White individuals. These findings raise important questions regarding which factors may explain this ...
Vestibular Sensory Conflict During Postural Control, Freezing of Gait, and Falls in Parkinson’s Disease
(John Wiley & Sons, Inc., 2022-11)
BackgroundThe vestibular system has been implicated in the pathophysiology of episodic motor impairments in Parkinson’s disease (PD), but specific evidence remains lacking.ObjectiveWe investigated the relationship between ...
Serotonin Transporter Imaging in Multiple System Atrophy and Parkinson’s Disease
(John Wiley & Sons, Inc., 2022-11)
BackgroundBoth Parkinson’s disease (PD) and multiple system atrophy (MSA) exhibit degeneration of brainstem serotoninergic nuclei, affecting multiple subcortical and cortical serotoninergic projections. In MSA, medullary ...
BayeStab: Predicting effects of mutations on protein stability with uncertainty quantification
(John Wiley & Sons, Inc., 2022-11)
Predicting protein thermostability change upon mutation is crucial for understanding diseases and designing therapeutics. However, accurately estimating Gibbs free energy change of the protein remained a challenge. Some ...
Recombinant human platelet-derived growth factor improves root coverage of a collagen matrix for multiple adjacent gingival recessions: A triple-blinded, randomized, placebo-controlled trial
(Wiley Periodicals, Inc.Blackwell Publishing Ltd, 2022-11)
AimTo evaluate the efficacy of recombinant human platelet-derived growth factor (rhPDGF)-BB combined with a cross-linked collagen matrix (CCM) for the treatment of multiple adjacent gingival recession type 1 defects (MAGRs) ...
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update
(Wiley Periodicals, Inc., 2022-11)
Adopting artificial intelligence in dental education: A model for academic leadership and innovation
(Jossey-Bass IncWiley Periodicals, Inc., 2022-11)
IntroductionThe continual evolution of dental education, dental practice and the delivery of optimal oral health care is rooted in the practice of leadership. This paper explores opportunities and challenges facing dental ...
Use of blood pressure measurements extracted from the electronic health record in predicting Alzheimer’s disease: A retrospective cohort study at two medical centers
(Wiley, 2022-11)
IntroductionStudies investigating the relationship between blood pressure (BP) measurements from electronic health records (EHRs) and Alzheimer’s disease (AD) rely on summary statistics, like BP variability, and have only ...