Now showing items 41-50 of 2837
Addressing Medication Nonadherence Using Mobile Phone-Based Tailored Messaging.
(2014)
While numerous treatments exist to manage diabetes, adherence to guideline-recommended medications remains suboptimal. Both tailoring health messages and text messaging have been observed to improve medication adherence, ...
Human N ‐acetylation genotype determination with urinary caffeine metabolites
(Wiley Periodicals, Inc., 1990-04)
Effects of Gravity on Gastric Emptying, Intestinal Transit, and Drug Absorption
(Wiley Periodicals, Inc.Blackwell Publishing Ltd, 1991-10)
Antiarrhythmic and electrophysiologic actions of clofilium in experimental canine models
(Elsevier, 1985-10-08)
Clofilium was studied in three experimental models. In non-ischemic and chronically infarcted canine hearts, clofilium (0.5-2 mg/kg) produced a dose-dependent increase in electrical ventricular fibrillation threshold (VFT), ...
Access to Investigational Drugs: FDA Expanded Access Programs or “Right‐to‐Try” Legislation?
(Wiley Periodicals, Inc., 2015-10)
PurposeThe Food and Drug Administration Expanded Access (EA) program and “Right‐to‐Try” legislation aim to provide seriously ill patients who have no other comparable treatment options to gain access to investigational ...
Contribution of Renal and Non‐Renal Clearance on Increased Total Clearance of Adalimumab in Glomerular Disease
(Wiley Periodicals, Inc., 2013-09)
The contribution of renal and non‐renal clearance toward targeted concentrations and/or effects of therapeutic proteins in nephrotic patients are unknown. This study dissected the contribution of clearance pathways to ...
Comparison of in vitro – in vivo extrapolation of biliary clearance using an empirical scaling factor versus transport‐based scaling factors in sandwich‐cultured rat hepatocytes
(Wiley Subscription Services, Inc., A Wiley Company, 2013-08)
Biliary clearance (CL b ) is often underestimated by in vitro – in vivo extrapolation from sandwich‐cultured hepatocytes (SCHs). The objective of this study was to compare the performance of a universal correction factor ...
A mathematical model to describe drug release from thin topical applications
(Elsevier, 1989-12-01)
Release of a thin topical application of a drug is modeled by transient diffusion between the application, the underlying stratum corneum, and a receptor. Cases treated include sudden contact of the application with drug-free ...
Advances in Thrombolytic Therapy for Acute Myocardial Infarction
(Blackwell Publishing LtdWiley Periodicals, Inc., 1987-10)
Plasma protein binding of prednisolone in normal volunteers and arthritic patients
(Springer-Verlag, 1979-11)
The plasma binding of prednisolone was studied in twenty normal volunteers and twenty rheumatoid arthritis patients. An in vitro assessment of the binding following the addition of prednisolone, prednisone, and hydrocortisone ...