Now showing items 171-180 of 209
The use of d -amphetamine pellet implantation as a model for d -amphetamine tolerance in the mouse
(Springer-Verlag, 1973-09)
The use of d -amphetamine pellet implantation as a method for producing rapid central drug tolerance was investigated. Mice were implanted with d -amphetamine pellets containing 2 mg of drug and were challenged 24 h later, ...
Opioid receptor subtype-specific cross-tolerance to the effects of morphine on schedule-controlled behavior in mice
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1988-10)
Key-press responding of mice was maintained under a fixed-ratio (FR) 30-response schedule of food presentation. Successive 3-min periods during which the experimental chamber was illuminated and the schedule was in effect ...
Discriminative stimulus effects of etorphine in rhesus monkeys
(Springer-Verlag, 1981-03)
Two rhesus monkeys were trained to discriminate the IM injection of etorphine (0.001 mg/kg) from saline in a task in which 20 consecutive responses on one of two levers resulted in food delivery. In both monkeys, etorphine ...
Effects of contextual or olfactory cues previously paired with morphine withdrawal on behavior and pain sensitivity in the rat
(Springer-Verlag, 2001-08)
Rationale: Pavlovian conditioning processes have been accorded an important role in maintaining persistent opiate administration. At least one locus for this contribution is during opiate withdrawal. These experiments ...
Differential development of behavioral tolerance and the subsequent hedonic effects of alcohol in AA and ANA rats
(Springer-Verlag, 2000-09)
Rationale: There at least two ways in which tolerance development to alcohol's behavioral effects could interact with its subsequent intake: 1) tolerance to alcohol's reward or reinforcing effects per se could lead to ...
Expression of behavioral sensitization to ethanol by DBA/2J mice: the role of NMDA and non-NMDA glutamate receptors
(Springer-Verlag, 2003-05)
Rationale. Behavioral sensitization has been accorded a central role in contemporary theories of drug addiction. Accordingly, a substantial effort has been made to determine the processes mediating sensitization to ...
Autonomic and psychic effects of yohimbine hydrochloride
(Springer-Verlag, 1961-03)
Yohimbine in a dose of 0.5 mg/kg has been given to 51 male mental hospital subjects and nine normal volunteers.
Rebuttal of comments by Griffiths, Lader and Greenblatt to Review by Woods and Winger
(Springer-Verlag, 1995-03)
Chronic administration of the delta opioid receptor agonist (+)BW373U86 and antidepressants on behavior in the forced swim test and BDNF mRNA expression in rats
(Springer-Verlag, 2005-11)
Selective delta opioid receptor agonists have been shown to produce antidepressant-like behavioral effects and increase brain-derived neurotrophic factor (BDNF) mRNA expression when given acutely, but the chronic effects ...
Naloxone blockade of amphetamine place preference conditioning
(Springer-Verlag, 1991-06)
Amphetamine and naloxone were examined in place conditioning, in order to study possible interactions between endogenous opioids and catecholamines in reinforcement. After initial preferences were determined, animals were ...