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Key Experimental Approaches in DNA Nanotechnology
(Alan R. LissWiley Periodicals, Inc., 2002-06)
DNA nanotechnology combines unusual DNA motifs with sticky‐ended cohesion to build polyhedral objects, topological targets, nanomechanical devices, and both crystalline and aperiodic arrays. The goal of DNA nanotechnology ...
Children with hyperdiploid but not triple trisomy (+4,+10,+17) acute lymphoblastic leukemia have an increased incidence of extramedullary relapse on current therapies: A single institution experience
(Wiley Subscription Services, Inc., A Wiley Company, 2008-01)
To evaluate the outcome of children with high hyperdiploid acute lymphoblastic leukemia (hHDALL) treated at the author's institution. One hundred thirty-five consecutive children with B-precursor ALL were diagnosed between ...
Probing RNA Structure with Chemical Reagents and Enzymes
(Wiley Periodicals, Inc., 2000-02)
This unit provides thorough coverage of the most useful chemical and enzyme probes that can be used to examine RNA secondary and tertiary structure. Footprinting methods are presented using dimethyl sulfate, diethyl ...
Temporal pattern of C1q deposition after transient focal cerebral ischemia
(Wiley Subscription Services, Inc., A Wiley Company, 2006-04)
Recent studies have focused on elucidating the contribution of individual complement proteins to post-ischemic cellular injury. As the timing of complement activation and deposition after cerebral ischemia is not well ...
Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
Current treatment protocol for postoperative pain is to infuse anesthetic solution around nerves or into the epidural space. This clinical practice is beset by the short duration of the anesthetic effect unless the infusion ...
Oligoribonucleotides with 2′‐O‐(tert‐Butyldimethylsilyl) Groups
(Wiley Periodicals, Inc.IRL Press,, 2000-07)
The chemical synthesis of oligoribonucleotides on solid support is routinely performed via the phosphoramidite method. However, the additional 2‐OH function of the ribofuranosyl sugar requires suitable protection during ...
More TORC for the gluconeogenic engine
(Wiley Subscription Services, Inc., A Wiley Company, 2006-03)
Hepatic gluconeogenesis plays a key role in the maintenance of glucose homeostasis. The hormone glucagon stimulates this process, whereas insulin and adiponectin are inhibitory. In a recent report, Koo et al identify the ...
Determination of Binding Mode: Intercalation
(Academic PressWiley Periodicals, Inc., 2000-02)
A small molecule can be assumed to bind to DNA by intercalation between base pairs if it causes lengthening and unwinding of the DNA helix and undergoes changes in its spectral properties, such as DNA‐induced hypochromism ...
An Empirical Model for Estimating Remediation Costs at Contaminated Sites
(Kluwer Academic Publishers; Springer Science + Business Media, Inc., 2005-10)
A model for estimating the remediation costs at contaminated sites is developed, in which the predictor variable is a composite of surface, subsurface, and contaminant risk factors. Calibration of the model is performed ...