Now showing items 21-30 of 843
Haplotype variation and genotype imputation in African populations
(Wiley Subscription Services, Inc., A Wiley Company, 2011-12)
Sub‐Saharan Africa has been identified as the part of the world with the greatest human genetic diversity. This high level of diversity causes difficulties for genome‐wide association (GWA) studies in African populations—for ...
Characterization of A. baumannii Environmental Survival and Biofilm Formation and the Impact on Environmental Transmission.
(2015)
Acinetobacter baumannii is a gram-negative, opportunistic pathogen primarily affecting the critically ill, causing 3% of all nosocomial-related deaths in the United States. A. baumannii’s successful environmental survival ...
Variable selection in monotone single‐index models via the adaptive LASSO
(SpringerWiley Periodicals, Inc., 2013-09-30)
We consider the problem of variable selection for monotone single‐index models. A single‐index model assumes that the expectation of the outcome is an unknown function of a linear combination of covariates. Assuming ...
Quantifying Prefibrillar Amyloids in vitro by Using a “Thioflavin-Like” Spectroscopic Method
(WILEY-VCH Verlag, 2010-09-03)
In Alzheimer's disease (AD) and other neurodegenerative disorders, proteins accumulate into ordered aggregates, called amyloids. Recent evidence suggests that these structures include both large, insoluble fibrils and ...
Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels
(Wiley Periodicals, Inc., 2017-12)
The accuracy of genotype imputation depends upon two factors: the sample size of the reference panel and the genetic similarity between the reference panel and the target samples. When multiple reference panels are not ...
Comparison of methods for estimating the effect of salvage therapy in prostate cancer when treatment is given by indication
(Wiley Periodicals, Inc., 2014-01-30)
Highlights of B/D‐HPP and HPP Resource Pillar Workshops at 12th Annual HUPO World Congress of Proteomics
(Wiley Periodicals, Inc., 2014-05)