Now showing items 3471-3480 of 3511
Evaluating an Alternative Endothelial Cell Source to Vascularize Engineered Tissue Constructs
(2018)
A major translational challenge in the fields of therapeutic angiogenesis and regenerative medicine is the need to create functional microvasculature. Cell-based strategies to promote neovascularization have been widely ...
Isolation and Analysis of Circulating Tumor Cells in Genitourinary Cancers
(2017)
While accessible by a relatively noninvasive blood draw, circulating tumor cells (CTCs) remain difficult to study because of their rarity and their presence amongst the billions of surrounding normal blood cells. Of ...
Investigation of the Optical Properties of Novel Organic Macromolecules for Solar Cell Applications.
(2015)
The search for renewable energy sources to replace fossil fuel has been a major research focus in the energy sector. The sun, with its vast amount of energy, remains the most abundant and ubiquitous energy source that far ...
Selective Wettability Membranes and Surfaces for the Separation of Oil-Water Mixtures, Extractions, and Fouling Prevention
(2018)
The separation of miscible and immiscible liquid mixtures is one of the most widely utilized unit operations in the world. The energy-efficient separation of immiscible oil-water mixtures is critical for a wide variety ...
PSM Small Peptide Toxins Form Functional Bacterial Amyloids in the Staphylococcus aureus Biofilm Matrix.
(2014)
Staphylococcus aureus is a Gram-positive opportunistic pathogen colonizing mammalian hosts. Like many bacteria, S. aureus forms multicellular aggregates called biofilms. Biofilms are surface-associated communities of ...
Probing Heat Transport and Energy Conversion at the Atomic and Single Molecule Scale
(2018)
The study of heat transport and energy conversion constitutes an important subject in modern physics and engineering research. The widely-applied Fourier’s and Planck’s laws have proven to be very useful to describe heat ...
Systematic Improvement of Quantification and Formulation of Synthetic Protein Nanoparticles for Gene Delivery
(2022)
Gene therapy is a promising field for the generation of new and more effective therapies, but its application is stymied by the lack of safe and efficient delivery vehicles. Furthermore, gene delivery system optimization ...
Investigating and Engineering Polymeric Interfaces: Elucidating the Swelling of Polyelectrolyte Brushes and Brush Bilayer Thin Films and the Development of Novel Electrospun Polymer Membranes for the Catalysis of Biodiesel
(2020)
In this thesis, we examine a variety of engineered interfaces: polymer thin films—in the morphologies of brushes and LbL bilayers—and polymer membranes.
First, this work investigates the swelling/de-swelling behavior of ...
Information Processing under Physiological Pulsatile Stimulation in a G-protein Coupled Signaling Pathway
(2016)
The cellular microenvironment is often dynamic, and several physiological ligands are released in pulsatile bursts. The main hypothesis driving this study is that cells are able to discern these time-varying dynamic inputs ...
Design Principles for Nanocrystal Assembly Using Anisotropic Building Blocks
(2020)
Self-assembly of soft matter is a phenomena that can be influenced by multiple factors including particle shape, ligand decoration and thermodynamic properties such as temperature and pressure. In this highly anisotropic ...