Now showing items 11-20 of 666
Variable selection in monotone single‐index models via the adaptive LASSO
(SpringerWiley Periodicals, Inc., 2013-09-30)
We consider the problem of variable selection for monotone single‐index models. A single‐index model assumes that the expectation of the outcome is an unknown function of a linear combination of covariates. Assuming ...
Engineering Specific Cross‐Links in Nucleic Acids Using Glycol Linkers
(Wiley Periodicals, Inc., 2000-02)
One of the most convenient methods for generating oligonucleotides possessing intra‐ or interstrand cross‐links is through incorporation of oligoethylene glycol bridges by solid‐phase synthesis. The reagents are commercially ...
Comparison of methods for estimating the effect of salvage therapy in prostate cancer when treatment is given by indication
(Wiley Periodicals, Inc., 2014-01-30)
Key Experimental Approaches in DNA Nanotechnology
(Alan R. LissWiley Periodicals, Inc., 2002-06)
DNA nanotechnology combines unusual DNA motifs with sticky‐ended cohesion to build polyhedral objects, topological targets, nanomechanical devices, and both crystalline and aperiodic arrays. The goal of DNA nanotechnology ...
Probing RNA Structure with Chemical Reagents and Enzymes
(Wiley Periodicals, Inc., 2000-02)
This unit provides thorough coverage of the most useful chemical and enzyme probes that can be used to examine RNA secondary and tertiary structure. Footprinting methods are presented using dimethyl sulfate, diethyl ...
Temporal pattern of C1q deposition after transient focal cerebral ischemia
(Wiley Subscription Services, Inc., A Wiley Company, 2006-04)
Recent studies have focused on elucidating the contribution of individual complement proteins to post-ischemic cellular injury. As the timing of complement activation and deposition after cerebral ischemia is not well ...
Time course of tinnitus development following noise exposure in mice
(Wiley Subscription Services, Inc., A Wiley Company, 2012-07)
Gap‐induced prepulse inhibition of acoustic startle (GPIAS) has been used in rats and mice to study the problem of tinnitus. The current study demonstrates that similar methods can be used to study the temporal development ...