Now showing items 39761-39770 of 41314
Small Molecule Modulators of Transcription.
(2010)
Transcriptional activators are key components in the regulation of gene expression, being critical for precise, high fidelity transcription. Misregulation of transcription is a hallmark of many diseases, including diabetes, ...
On Improving the Effectiveness of Control Signals from Chronic Microelectrodes for Cortical Neuroprostheses.
(2009)
Using microelectrodes, we can record neural signals which can eventually be used to control cortical neuroprostheses for assisting people with spinal-cord trauma, stroke deficits, amyotrophic lateral sclerosis (ALS), and ...
Femtosecond Coherent Control of Quantum Systems in Liquid Phase.
(2008)
Femtochemistry is a mature field which now moves beyond observing molecular motion, towards laser control of chemical reactions. In early molecular control experiments success meant simply increasing the reaction yield. ...
Models of Twisted K-theory.
(2008)
This thesis concerns geometrical models in complete generality of twistings in complex K-theory, in particular of higher twistings. In the first three chapters we treat the non-equivariant situation. In the rest of the ...
An All-Sky Search for Continuous Gravitational Waves.
(2009)
Gravitational radiation is a direct consequence of general relativity, yet to this day only indirect
confirmation of its existence has been obtained.
LIGO is an experiment that aims to detect gravitational waves by comparing ...
Inducible Regulation of Gastrin Gene Expression During Helicobacter Pylori Infection.
(2009)
Gastrin is a peptide hormone expressed in the adult antral stomach. Gastrin is a potent regulator of acid secretion and is a growth factor required for the maintenance of gastrointestinal physiology. The expression of ...
Semiparametric Methods for Estimating Cumulative Treatment Effects in the Presence of Non-proportional Hazards and Dependent Censoring.
(2008)
The research in this thesis focuses on methods for estimating the cumulative treatment effect on time to an event in the setting when the treatment-specific hazards are not proportional. In clinical studies of time to event ...
Smooth Cocycles over Homogeneous Dynamical Systems.
(2010)
In this thesis, we study actions by higher-rank abelian groups on quotients of semisimple Lie groups with finite center. First, we consider actions arising from the flows of two commuting elements of the Lie algebra---one ...
Quantitative Thermochronology and Interpretation of Exhumation in the Central Nepalese Himalaya.
(2008)
Quantifying erosional and tectonic processes that exhume rock in convergent orogens
is an essential step toward understanding connections between climate and
tectonics. This work utilizes 3-D numerical models to address ...
Contributions to Reliability and Lifetime Data Analysis.
(2007)
This dissertation deals with problems in reliability and lifetime data analysis. The first part focuses on the study of graphical estimators from probability plots with right censored data. The second part deals with ...