Now showing items 21-30 of 88
(1) The Relationship of Protein Expression and Cell Division, (2) 3D Imaging of Cells Using Digital Holography, and (3) General Chemistry Enrollment at University of Michigan.
(2012)
Chapter 1: We evaluated the relationship between cell division and protein expression when using commercial poly(ethylenimine) (PEI)-based polyplexes. The membrane dye PKH26 was used to assess cell division, and cyan ...
Ultrafast Hydration Dynamics Near Extended Macromolecular Interfaces
(2019)
Liquid water is arguably the most complex, but interesting chemical, enabling development and sustenance of life. The tetrahedral geometry of the water molecule allows the formation of a dense network of hydrogen bonds ...
Predicting the Formation Pathways and Morphologies of Oxygenated Carbonaceous Nanoparticle Precursors in Premixed Flames
(2017)
Organic nanoparticles are an inevitable by-product of combustion phenomena that have deleterious health and environmental effects. They are carcinogenic because they damage biological cells due to their small size and their ...
Fundamental and Applied Electrochemistry for Photonic Applications
(2020)
Photonic devices that selectively transmit or reflect light are highly desirable in a wide variety of applications, including energy harvesting, aesthetic decorations and optical displays. However, most of these high ...
Chemical Modulators of Heat Shock Protein 70 (Hsp70) Validate this Molecular Chaperone as a Target for Tauopathy
(2016)
Misregulation of tau, an intrinsically disordered protein, is implicated in Alzheimer’s disease (AD) and more than 15 related tauopathies. These diseases are characterized by the accumulation of tau aggregates into insoluble ...
Synthesis of Cardiotonic Steroids Oleandrigenin and Rhodexin B and Studies Toward the Synthesis of Bufalin
(2021)
Organic chemistry is an ever-evolving field, which produces constant development of new synthetic methods featuring novel technologies. This is critical in driving innovation, especially in total synthesis. Total synthesis ...
Selectivity Mechanisms Employed by Flavin-Dependent Monooxygenases
(2021)
Nature is an incredible source of inspiration for the discovery and subsequent development of new bioactive compounds. Unfortunately, the synthesis of these molecules is often prohibitively complex, requiring the installation ...
Development of Novel Small Molecule Inhibitors of Neurotropic Alphavirus Replication.
(2014)
Emerging mosquito-borne viruses (arboviruses) constitute a large public health risk because of the ubiquity of mosquitoes and the potential for mosquito-human transmission. Neurotropic alphaviruses are of particular interest ...
Online Single Particle Chemical Characterization Of Aerosol Populations in Remote Environments
(2017)
Atmospheric aerosols have significant impacts on air quality, climate, and human health, yet analytical and logistical challenges have limited our ability to measure these aerosol particles, particularly in remote regions. ...
Nanopores with Fluid Walls for Characterizing Proteins and Peptides.
(2012)
Nanopore-based, resistive-pulse sensing is a simple single-molecule technique, is label free, and employs basic electronic recording equipment. This technique shows promise for rapid, multi-parameter characterization of ...