Now showing items 11-17 of 17
Microfluidic Technologies for Bioanalytical Chemistry: Advancing Epigenetic Profiling via Chromatin Immunoprecipitation in Droplets
(2019)
Beyond the linear sequence of the genome, the epigenome dynamically controls chromatin remodeling and transcriptional poise without inducing changes in DNA sequence. These epigenetic mechanisms, particularly modifications ...
From Small Molecules to Polymers: Linear and Nonlinear Optical Properties of Organic Conjugated Systems for Solar Applications
(2018)
The world is seeing rapid population growth and with this growth, energy demands have soared. Traditionally, fossil fuels have been used to meet these demands, but extraction of fossil fuels is detrimental to the environment, ...
Understanding the Solution Phase Chemistry and Solid State Thermodynamic Behavior of Pharmaceutical Cocrystals.
(2012)
This dissertation focuses on the thermodynamic stability and solubility of pharmaceutical cocrystals. Specifically, the objectives are to; (i) investigate the influence of coformer properties such as solubility and ionization ...
Probing Heat Transport and Energy Conversion at the Atomic and Single Molecule Scale
(2018)
The study of heat transport and energy conversion constitutes an important subject in modern physics and engineering research. The widely-applied Fourier’s and Planck’s laws have proven to be very useful to describe heat ...
Theoretical and Experimental Study of Fuel Injector Tip Wetting as a Source of Particulate Emissions in Gasoline Direct-Injection Engines
(2019)
Gasoline fuel film deposited on the tip of a fuel injector, i.e. injector tip wetting, has been identified as a significant source of particulate emissions at some operating conditions of gasoline direct-injection engines. ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Multicompartmental Biomaterials via Electrohydrodynamic Co-jetting.
(2011)
The synthesis and theranostic applications of biodegradable anisotropic materials are described in this dissertation. Precise nano- and micro-scale control of the architecture of biodegradable polymeric materials is highly ...