Now showing items 21-30 of 40
Systems analysis of dynamic transcription factor activity identifies targets for treatment in Olaparib resistant cancer cells
(Wiley Periodicals, Inc.Systems Biology, 2017-09)
The development of resistance to targeted therapeutics is a challenging issue for the treatment of cancer. Cancers that have mutations in BRCA, a DNA repair protein, have been treated with poly(ADP‐ribose) polymerase (PARP) ...
Alteration of the growth rate and lag time of Leuconostoc mesenteroides NRRL-B523
(John Wiley & Sons, Inc., 2001-03-20)
Bacterial profile modification is an important enhanced oil recovery technique used to direct injected water into a reservoir's low permeability zone containing trapped crude oil. During water flooding, the use of bacteria ...
Production of cellulosic organic acids via synthetic fungal consortia
(Wiley Periodicals, Inc., 2018-04)
Consolidated bioprocessing (CBP) is a potential breakthrough technology for reducing costs of biochemical production from lignocellulosic biomass. Production of cellulase enzymes, saccharification of lignocellulose, and ...
Statistical Analysis of Multiplex Brain Gene Expression Images
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2002-10)
Analysis of variance (ANOVA) was employed to investigate 9,000 gene expression patterns from brains of both normal mice and mice with a pharmacological model of Parkinson's disease (PD). The data set was obtained using ...
Monitoring granule formation in anaerobic upflow bioreactors using oligonucleotide hybridization probes
(Wiley Subscription Services, Inc., A Wiley Company, 2006-06-20)
The process of granule formation in upflow anaerobic sludge blanket (UASB) reactors was studied using oligonucleotide hybridization probes. Two laboratory-scale UASB reactors were inoculated with sieved primary anaerobic ...
William Hogarth, Unwitting Neurochemist?
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 2000-10)
William Hogarth's famous etching Gin Lane is often used to illustrate the debilitating results of alcohol addiction. Less well known is the companion etching Beer Street in which death, murder and squalor are replaced by ...
Sensitive detection of glucagon aggregation using amyloid fibril‐specific antibodies
(Wiley Periodicals, Inc., 2019-08)
Sensitive detection of protein aggregates is important for evaluating the quality of biopharmaceuticals and detecting misfolded proteins in several neurodegenerative diseases. However, it is challenging to detect extremely ...
Effects of the antimicrobial tylosin on the microbial community structure of an anaerobic sequencing batch reactor
(Wiley Subscription Services, Inc., A Wiley Company, 2011-02)
The effects of the antimicrobial tylosin on a methanogenic microbial community were studied in a glucose-fed laboratory-scale anaerobic sequencing batch reactor (ASBR) exposed to stepwise increases of tylosin (0, 1.67, and ...
Assessing the ability of human endothelial cells derived from induced‐pluripotent stem cells to form functional microvasculature in vivo
(Wiley Periodicals, Inc., 2019-02)
Forming functional blood vessel networks is a major clinical challenge in the fields of tissue engineering and therapeutic angiogenesis. Cell‐based strategies to promote neovascularization have been widely explored, but ...
384 hanging drop arrays give excellent Z ‐factors and allow versatile formation of co‐culture spheroids
(Wiley Subscription Services, Inc., A Wiley Company, 2012-05)
We previously reported the development of a simple, user‐friendly, and versatile 384 hanging drop array plate for 3D spheroid culture and the importance of utilizing 3D cellular models in anti‐cancer drug sensitivity ...