Now showing items 1-8 of 8
Retrievable hydrogels for ovarian follicle transplantation and oocyte collection
(American Cancer SocietyWiley Periodicals, Inc., 2018-08)
Cancer survivorship rates have drastically increased due to improved efficacy of oncologic treatments. Consequently, clinical concerns have shifted from solely focusing on survival to quality of life, with fertility ...
Evaluation of encapsulating and microporous nondegradable hydrogel scaffold designs on islet engraftment in rodent models of diabetes
(Wiley Periodicals, Inc., 2018-09)
Islet transplantation is a promising therapeutic option for type 1 diabetes mellitus, yet the current delivery into the hepatic portal vasculature is limited by poor engraftment. Biomaterials have been used as a means to ...
Dynamic microRNA activity identifies therapeutic targets in trastuzumab‐resistant HER2+ breast cancer
(Wiley Periodicals, Inc.Springer, 2018-10)
MicroRNAs (miRNAs) are implicated in numerous physiologic and pathologic processes, such as the development of resistance to chemotherapy. Determining the role of miRNAs in these processes is often accomplished through ...
Production of cellulosic organic acids via synthetic fungal consortia
(Wiley Periodicals, Inc., 2018-04)
Consolidated bioprocessing (CBP) is a potential breakthrough technology for reducing costs of biochemical production from lignocellulosic biomass. Production of cellulase enzymes, saccharification of lignocellulose, and ...
The Wnt Transcriptional Switch: TLE Removal or Inactivation?
(Wiley Periodicals, Inc., 2018-02)
Methodological Advances for Drug Discovery and Protein Engineering
(2018)
Designing and engineering molecules that have specified properties not only test our understanding of nature but also play an important role in improving both human health and industrial productivity. Two such examples are ...
Inside or Out: Characterizing petrobactin use by Bacillus anthracis
(2018)
Bacillus anthracis is a Gram-positive, spore-forming bacillus and causes the disease anthrax. Anthrax is a deadly infection that begins with phagocytosis of a B. anthracis spore by an antigen presenting cell and ends when ...
Sexual Deprivation, Emotion, and Longevity: Neuropeptidergic Regulation of Aging in Drosophila
(2018)
While researchers often focus on the brain as a victim of aging via neurodegenerative diseases, recent work has demonstrated that the aging process is regulated by neural mechanisms. Thus, we asked which mechanisms and ...