Now showing items 1-6 of 6
Combinatorial lentiviral gene delivery of pro‐oligodendrogenic factors for improving myelination of regenerating axons after spinal cord injury
(Wiley Periodicals, Inc., 2019-01)
Spinal cord injury (SCI) results in paralysis below the injury and strategies are being developed that support axonal regrowth, yet recovery lags, in part, because many axons are not remyelinated. Herein, we investigated ...
Sensitive detection of glucagon aggregation using amyloid fibril‐specific antibodies
(Wiley Periodicals, Inc., 2019-08)
Sensitive detection of protein aggregates is important for evaluating the quality of biopharmaceuticals and detecting misfolded proteins in several neurodegenerative diseases. However, it is challenging to detect extremely ...
Assessing the ability of human endothelial cells derived from induced‐pluripotent stem cells to form functional microvasculature in vivo
(Wiley Periodicals, Inc., 2019-02)
Forming functional blood vessel networks is a major clinical challenge in the fields of tissue engineering and therapeutic angiogenesis. Cell‐based strategies to promote neovascularization have been widely explored, but ...
Biological Pathway Specificity in the Cell—Does Molecular Diversity Matter?
(Wiley Periodicals, Inc.Simon and Schuster, 2019-08)
Fluid shear stress stimulates breast cancer cells to display invasive and chemoresistant phenotypes while upregulating PLAU in a 3D bioreactor
(Wiley Periodicals, Inc., 2019-11)
Breast cancer cells experience a range of shear stresses in the tumor microenvironment (TME). However most current in vitro three‐dimensional (3D) models fail to systematically probe the effects of this biophysical stimuli ...