Now showing items 1-10 of 53
On Demand Light‐Degradable Polymers Based on 9,10‐Dialkoxyanthracenes
(Wiley Periodicals, Inc., 2020-08)
Light induced degradation of polymers has drawn increasing interest due to the need for externally controllable modulation of materials properties. However, the portfolio of polymers, that undergo precisely controllable ...
Cover Feature: Flavin‐Dependent Monooxygenases NotI and NotI′ Mediate Spiro‐Oxindole Formation in Biosynthesis of the Notoamides (ChemBioChem 17/2020)
(Wiley Periodicals, Inc., 2020-09-01)
Flavin‐Dependent Monooxygenases NotI and NotI′ Mediate Spiro‐Oxindole Formation in Biosynthesis of the Notoamides
(Wiley Periodicals, Inc., 2020-09-01)
The fungal indole alkaloids are a unique class of complex molecules that have a characteristic bicyclo[2.2.2]diazaoctane ring and frequently contain a spiro‐oxindole moiety. While various strains produce these compounds, ...
Neutralization of IL- 10 produced by B cells promotes protective immunity during persistent HCV infection in humanized mice
(Wiley Periodicals, Inc., 2020-09)
Chronic HCV infection can lead to cirrhosis and is associated with increased mortality. Interleukin (IL)- 10- producing B cells (B10 cells) are regulatory cells that suppress cellular immune responses. Here, we aimed to ...
Enzyme Scaffolds with Hierarchically Defined Properties via 3D Jet Writing
(Wiley Periodicals, Inc.Millersville, PA, 2020-09)
The immobilization of enzymes into polymer hydrogels is a versatile approach to improve their stability and utility in biotechnological and biomedical applications. However, these systems typically show limited enzyme ...
Stereoselective β‐Mannosylation via Anomeric O‐Alkylation with L‐Sugar‐Derived Electrophiles
(Wiley Periodicals, Inc., 2021-12-28)
A total synthesis of the trisaccharide repeat unit of Salmonella serogroup E1 O‐antigen is reported. This synthesis features a key β‐mannosylation reaction through a cesium carbonate‐mediated anomeric O‐alkylation of a ...
Spatial arrangement of proteins in planar and curved membranes by PPM 3.0
(John Wiley & Sons, Inc., 2022-01)
Cellular protrusions, invaginations, and many intracellular organelles have strongly curved membrane regions. Transmembrane and peripheral membrane proteins that induce, sense, or stabilize such regions cannot be properly ...
Use of a mobile app to capture supplemental health information during pregnancy: Implications for clinical research
(John Wiley & Sons, Inc., 2022-01)
PurposeMobile applications (- apps- ) may be efficient tools for improving the quality of clinical research among pregnant women, but evidence is sparse. We assess the feasibility and generalizability of a mobile app for ...
Facile Fabrication of Anisotropic Multicompartmental Microfibers Using Charge Reversal Electrohydrodynamic Co‐Jetting
(Wiley Periodicals, Inc., 2022-01)
Anisotropic microstructures are utilized in various fields owing to their unique properties, such as reversible shape transitions or on‐demand and sequential release of drug combinations. In this study, anisotropic ...
Curcumin downregulates the PI3K–AKT–mTOR pathway and inhibits growth and progression in head and neck cancer cells
(John Wiley & Sons, Ltd., 2020-12)
Curcumin, a polyphenol isolated from the rhizome of Curcuma longa, has been studied because of its antioxidant, antimicrobial, and antiinflammatory properties. This study aimed to evaluate the effects of curcumin on head ...