Now showing items 1-10 of 141
Synaptotagmin‐7 enhances calcium‐sensing of chromaffin cell granules and slows discharge of granule cargos
(Wiley Periodicals, Inc., 2020-09)
Synaptotagmin‐7 (Syt‐7) is one of two major calcium sensors for exocytosis in adrenal chromaffin cells, the other being synaptotagmin‐1 (Syt‐1). Despite a broad appreciation for the importance of Syt‐7, questions remain ...
Differential propagation of ripples along the proximodistal and septotemporal axes of dorsal CA1 of rats
(John Wiley & Sons, Inc., 2020-09)
The functional connectivity of the hippocampus with its primary cortical input, the entorhinal cortex, is organized topographically. In area CA1 of the hippocampus, this leads to different functional gradients along the ...
Toward a “treadmill test” for cognition: Improved prediction of general cognitive ability from the task activated brain
(John Wiley & Sons, Inc., 2020-08-15)
General cognitive ability (GCA) refers to a trait‐like ability that contributes to performance across diverse cognitive tasks. Identifying brain‐based markers of GCA has been a longstanding goal of cognitive and clinical ...
Uncertainty versus prediction error in Pavlovian fear conditioning: Commentary on Walker et al. (2019)
(Wiley Periodicals, Inc., 2020-09)
cIMPACT‐NOW update 7: advancing the molecular classification of ependymal tumors
(LyonWiley Periodicals, Inc., 2020-09)
Advances in our understanding of the biological basis and molecular characteristics of ependymal tumors since the latest iteration of the World Health Organization (WHO) classification of CNS tumors (2016) have prompted ...
Phasic cholinergic signaling promotes emergence of local gamma rhythms in excitatory–inhibitory networks
(Wiley Periodicals, Inc.Academic Press, 2020-09)
Recent experimental results have shown that the detection of cues in behavioral attention tasks relies on transient increases of acetylcholine (ACh) release in frontal cortex and cholinergically driven oscillatory activity ...
Functional magnetic resonance imaging multivoxel pattern analysis reveals neuronal substrates for collaboration and competition with myopic and predictive strategic reasoning
(John Wiley & Sons, Inc., 2020-10-15)
Competition and collaboration are strategies that can be used to optimize the outcomes of social interactions. Research into the neuronal substrates underlying these aspects of social behavior has been limited due to the ...
Distribution of androgen receptor mRNA in the prepubertal male and female mouse brain
(Raven PressWiley Periodicals, Inc., 2021-12)
Androgens are steroid hormones that play a critical role in brain development and sexual maturation by acting upon both androgen receptors (AR) and estrogen receptors (ERα/β) after aromatization. The contribution of estrogens ...
Synaptotagmin- 11 inhibits spontaneous neurotransmission through vti1a
(Wiley Periodicals, Inc., 2021-11)
Recent work has revealed that spontaneous release plays critical roles in the central nervous system, but how it is regulated remains elusive. Here, we report that synaptotagmin- 11 (Syt11), a Ca2+- independent Syt isoform ...