Now showing items 1-10 of 12
Simultaneous Multislice Functional Magnetic Resonance Imaging.
(2016)
Functional magnetic resonance imaging (fMRI) is a valuable tool for mapping brain activity in many fields. Since functional activity is determined by temporal signal changes, undesired fluctuations from physiological motion ...
Intracortical Neural Probes with Post-Implant Self-Deployed Electrodes for Improved Chronic Stability.
(2015)
This thesis presents a new class of implantable intracortical neural probe with small recording electrodes that deploy away from a larger main shank after insertion. This concept is hypothesized to enhance the performance ...
Computational Electromagnetic Methods for Transcranial Magnetic Stimulation.
(2015)
Transcranial magnetic stimulation (TMS) is a noninvasive technique used both as a research tool for cognitive neuroscience and as a FDA approved treatment for depression. During TMS, coils positioned near the scalp generate ...
Control and Effect of Glial Cell Activation on the Microscale Chronic Neural Interface toward Dynamic Control of Neural Environment.
(2010)
The limited lifetime of neural implants continues to frustrate the progress of neuroscience research. Despite extensive research into the inflammatory process and the encapsulation cascade, there has been little attention ...
Strategies for Optimizing Information Extraction from Cortical Recordings.
(2011)
Penetrating neural probe technologies provide researchers with the capability to stimulate and record chemical and electrical signals in the brain. While present technology has yielded significant insight into the function ...
The Modulatory Effects of Visual Speech on Auditory Speech Perception: A Multi-Modal Investigation of How Vision Alters the Temporal, Spatial and Spectral Components of Speech
(2022)
Visual speech information, especially that provided by the mouth and lips, is important during face-to-face communication. This has been made more evident by the increased difficulty of speech perception because mask usage ...
Brain Tissue Response in Neurochemical Sampling: Microdialysis and Low-Flow Push-Pull Perfusion.
(2013)
Neurochemical sensing via sampling probes is essential for deciphering neuronal communication and enabling technologies to alleviate brain disorders such as mental illness and Parkinson’s. The brain tissue response associated ...
In Vitro and In Vivo Testing of Ultra-Small Gold Nanoparticles as a Novel Drug Delivery Platform for Enhancing the Brain Penetration and Receptor Binding Affiinity of Central Nervous System Drugs.
(2013)
The endothelial cells of brain capillaries form the so-called blood brain barrier (BBB) which protects the central nervous system (CNS) from the entry of neurotoxins and blood components. Consequently, more than 98% of ...
Characterization of Cerebral Hemodynamics Using a Computational Fluid Dynamics and Arterial Spin Labeling MRI Strategy: Applications in Cerebrovascular Occlusive Disease
(2021)
Cerebrovascular occlusive disease (CVOD) is a major risk factor for ischemic stroke and is characterized by the presence of stenosis in the arteries supplying the brain. The cerebral vasculature has an innate ability to ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...