Now showing items 1-10 of 21
Use of mycophenolate mofetil in steroid-dependent and -resistant nephrotic syndrome
(Springer-Verlag; IPNA, 2003-08)
Cyclosporin (Cs-A) is an effective treatment for difficult cases of nephrotic syndrome (NS), but its use can be complicated by renal toxicity and a high incidence of relapses after withdrawal. We reviewed the charts of 10 ...
Identification of the human CYS1 gene and candidate gene analysis in Boichis disease
(Springer-Verlag; IPNA, 2003-06)
Recessive mutations cause cystic kidney disease and a variable degree of biliary liver fibrosis in cpk mice. Recently, the responsible murine gene ( Cys1 ) was identified and expression in renal cilia demonstrated. Here ...
Medication errors and patient complications with continuous renal replacement therapy
(Springer-Verlag; IPNA, 2006-04-19)
Continuous renal replacement therapy (CRRT) is commonly used for renal support in the intensive care unit. While the risk of medication errors in the intensive care unit has been described, errors related specifically to ...
Dialysis therapy for children with acute renal failure: survey results
(Springer-Verlag; IPNA - International Pediatric Nephrology Association New York, USA, 2000-10)
We surveyed 123 pediatric nephrologists to investigate the current dialytic management of acute renal failure (ARF) in children. Data collected from 92 responding physicians revealed that hemodialysis (HD), peritoneal ...
Hypopnea in pediatric patients with obesity hypertension
(Springer-Verlag; IPNA, 2004-09)
Obesity is associated with the development of hypertension but it is still not clear why hypertension is not observed in all obese patients. Obesity is a risk factor for the development of obstructive sleep apnea syndrome ...
Glucose transporters in diabetic nephropathy
(Springer-Verlag; IPNA, 2005-04)
Changes in glucose transporter expression in glomerular cells occur early in diabetes. These changes, especially the GLUT1 increase in mesangial cells, appear to play a pathogenic role in the development of ECM expansion ...
Acute renal failure following deferoxamine overdose
(Springer-Verlag; IPNA, 2003-03)
A 17-year-old patient with sickle cell-beta thalassemia undergoing treatment with home iron chelation therapy inadvertently received ten times the recommended dose of intravenous deferoxamine. Acute renal failure (ARF) ...
Identification of the first AHI1 gene mutations in nephronophthisis-associated Joubert syndrome
(Springer-Verlag; IPNA, 2006-01)
Joubert syndrome (JBTS) is an autosomal recessive multisystem disease characterized by cerebellar vermis aplasia, mental retardation, muscular hypotonia, an irregular breathing pattern in the neonatal period and abnormal ...
Vitamin E therapy in IgA nephropathy: a double-blind, placebo-controlled study
(Springer-Verlag; IPNA, 2003-10)
IgA nephropathy is the world's most common primary glomerulonephropathy. Recent evidence in a rat model implicated excessive production of oxygen-free radicals in the pathogenesis and suggested that vitamin E-treatment ...
NPHS2 mutation associated with recurrence of proteinuria after transplantation
(Springer-Verlag; IPNA, 2004-05)
Mutations in the NPHS2 gene encoding podocin are associated with steroid-resistant nephrotic syndrome (SRNS) in childhood. Patients usually present with focal segmental glomerulosclerosis (FSGS). It is unclear to what ...