Now showing items 11-20 of 35
Embryonic regulation of histone ubiquitination the sea urchin
(Wiley Subscription Services, Inc., A Wiley Company, 1995)
We have used quantitative 2-D protein electrophoresis and immunoprecipitation to study the patterns of histone ubiquitination at 10 h and 36 h of embryonic development in Strongylocentrotus purpuratus. Variants csH2A, ΑH2A, ...
Aggression, anxiety and vocalizations in animals: GABA A and 5-HT anxiolytics
(Springer-Verlag, 1995-09)
A continuing challenge for preclinical research on anxiolytic drugs is to capture the affective dimension that characterizes anxiety and aggression, either in their adaptive forms or when they become of clinical concern. ...
Current benzodiazepine issues
(Springer-Verlag, 1995-03)
This article deals with some of the recent evidence bearing on the issues of the liability of benzodiazepines to lead to abuse, dependence, and adverse behavioral effects. Reviews of epidemiological, clinical and experimental ...
Psychiatric comorbidity of smoking and nicotine dependence
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1995-03)
Recent epidemiologic studies have revealed that comorbidity of psychiatric disorders is far more pervasive than previously suspected. Strong associations have been reported between specific substance use disorders and ...
Countercurrent gradient chromatography: A continuous focusing technique
(Wiley Subscription Services, Inc., A Wiley Company, 1995-12-05)
The continuous separation of proteins was performed in a countercurrent gradient chromatography (CGC) system. A magnetically stabilized fluidized bed (MSFB) was used to establish true countercurrent contact of a solid resin ...
Subcellular distribution of terminal α-D- and β-D-galactosyl residues in Ehrlich tumour cells studied by lectin-gold techniques
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1995-04)
We have studied by high resolution in situ light and electron microscopic lectin-gold techniques the subcellular distribution of α- d -Gal residues using the Griffonia simplicifolia I-B 4 isolectin and compared it with ...
The development of sensitization to the psychomotor stimulant effects of amphetamine is enhanced in a novel environment
(Springer-Verlag, 1995-02)
Two experiments were designed to assess the effect of a “novel” environment on the development of sensitization to the psychomotor activating effects of d -amphetamine. In the first experiment, rats with a unilateral ...
Long-term effects of brief antihypertensive treatment on systolic blood pressure and vascular reactivity in young genetically hypertensive rats
(Kluwer Academic Publishers; Springer Science+Business Media, 1995-06)
Recent studies have shown that angiotensin converting enzyme (ACE) inhibitor treatment in young spontaneously hypertensive rats (SHR) reduces blood pressure into adulthood. This study explored changes in vascular reactivity ...
Role of calcium channel blocking agents in the prevention of atherosclerosis
(Kluwer Academic Publishers; Springer Science+Business Media, 1995-01)
Calcium channel blocking agents, although effective and widely used in the symptomatic therapy of hypertension and ischemic heart disease, have an uncertain effect on the development of coronary atherosclerosis, plaque ...