Now showing items 11-20 of 5029
Λ-Dynamics free energy simulation methods
(Wiley Subscription Services, Inc., A Wiley Company, 2009-08)
Free energy calculations are fundamental to obtaining accurate theoretical estimates of many important biological phenomena including hydration energies, protein-ligand binding affinities and energetics of conformational ...
High levels of non-activated receptors in glucocorticoid-sensitive S49wt mouse lymphoma cells incubated with dexamethasone
(Elsevier, 1994-10)
Upon agonist binding the heteromeric glucocorticoid receptor complex under goes a conformational change (receptor activation). This event involves the dissociation of a dimer of 90 kDa heat shock proteins. Whereas receptor ...
Curing reaction and product properties of polysulfones terminated with active functional groups
(Wiley Subscription Services, Inc., A Wiley Company, 1991-11-20)
The curing processes of maleimide-terminated polyether sulfone oligomers ( M n from 1100 to 3000) and ethynyl-terminated polysulfone prepolymers ( M n from 2600 to 12000) were investigated by means of DSC. The ...
Relationship between the subunit structure of insulin receptor and its competence to bind insulin and undergo phosphorylation
(Elsevier, 1984-11-01)
Insulin receptor partially purified from human placenta by chromatography on immobilized wheat germ agglutinin was subjected to affinity cross linking to determine the relationship between the subunit structure of the ...
Expression and regulation of cytochrome P-450I genes (CYP1A1 and CYP1A2) in the rat alimentary tract
(Elsevier, 1992-12-29)
Cytochrome P-450 (P450) enzymes in the mucosa of the alimentary tract may be involved in the activation and/or inactivation of ingested xenobiotics and procarcinogens. Since the multiple P450 enzymes have overlapping ...
Thermodynamics of the monohydrogen difluorides V. Melting thermodynamics of NH4HF2
(Elsevier, 1976-03)
The heat capacity of ammonium hydrogen difluoride was extended from 300 to 450 K by adiabatic calorimetry in order to study the melting phenomenon and provide thermodynamics into the liquid region. The corrected enthalpy ...
Inhibition-mediating dopamine receptors and the control of intracranial reward
(Springer-Verlag, 1979-01)
A receptor selective agonist and antagonist of inhibition-mediating dopamine receptors (type II receptors) produced significant and dose-related alterations in bar-pressing for intracranial reward. Receptor inhibition by ...
Leukotriene C4 induces vasogenic cerebral edema in rats
(Elsevier, 1984-06)
Leukotriene C4 (LTC4) is reported to neither contract nor relax isolated human cerebra artdial strips (1), but in skin LTC4 will increase vascular permeability in post capillary venules, increase blood flow (2) and elicit ...
Lead isotope analyses of leached feldspars: Constraints on the early crustal history of the Grenville Orogen
(Elsevier, 1994-12)
Lead isotopic data on leached K-feldspars, plagioclases, and muscovite provide constraints on the premetamorphic evolution of the Grenville Orogen in Ontario and New York. A boundary between reworked Archean crust to the ...