Now showing items 21-30 of 57
The role of melano‐macrophage aggregates in the storage of mercury and other metals: An example from yelloweye rockfish (Sebastes ruberrimus)
(Lewis PublishersWiley Periodicals, Inc., 2015-08)
Melano‐macrophage aggregates, collections of specialized cells of the innate immune system of fish, are considered a general biomarker for contaminant toxicity. To elucidate further the relationship between macrophage ...
Effects of Acute and Sustained Pain Manipulations on Performance in a Visual‐Signal Detection Task of Attention in Rats
(ElsevierWiley Periodicals, Inc., 2015-06)
Preclinical ResearchPatients with pain often display cognitive impairment including deficits in attention. The visual‐signal detection task (VSDT) is a behavioral procedure for assessment of attention in rodents. Male ...
Improving accuracy of protein contact prediction using balanced network deconvolution
(Wiley Periodicals, Inc., 2015-03)
Residue contact map is essential for protein three‐dimensional structure determination. But most of the current contact prediction methods based on residue co‐evolution suffer from high false‐positives as introduced by ...
Kinetics and thermodynamics of metal‐binding to histone deacetylase 8
(Wiley Periodicals, Inc., 2015-03)
Histone deacetylase 8 (HDAC8) was originally classified as a Zn(II)‐dependent deacetylase on the basis of Zn(II)‐dependent HDAC8 activity in vitro and illumination of a Zn(II) bound to the active site. However, in vitro ...
Robust and Powerful Affected Sibpair Test for Rare Variant Association
(Wiley Periodicals, Inc., 2015-07)
Advances in DNA sequencing technology facilitate investigating the impact of rare variants on complex diseases. However, using a conventional case‐control design, large samples are needed to capture enough rare variants ...
Protein Structure and Function Prediction Using I‐TASSER
(Wiley Periodicals, Inc., 2015-12)
I‐TASSER is a hierarchical protocol for automated protein structure prediction and structure‐based function annotation. Starting from the amino acid sequence of target proteins, I‐TASSER first generates full‐length atomic ...
Copper and nickel partitioning with nanoscale goethite under variable aquatic conditions
(John Wiley & Sons, 2015-08)
Metal contaminated sediments can be toxic to aquatic organisms and are common in human‐dominated ecosystems, which results in metals being a leading cause of ecosystem impairment. Bioavailability of metals is influenced ...
Structure and Function of Protein-only RNase P.
(2015)
Transfer RNA is essential for deciphering the genetic code. Transcribed as a precursor, containing extra nucleotides on its 5’ and 3’ termini, tRNA must undergo several enzymatic processing steps before functioning in ...
IL‐12‐polarized Th1 cells produce GM‐CSF and induce EAE independent of IL‐23
(Wiley Periodicals, Inc., 2015-10)
Proteomics analysis of rough endoplasmic reticulum in pancreatic beta cells
(Wiley Periodicals, Inc., 2015-05)