Now showing items 31-40 of 158
Rapid communication : Inhibition of adenosine deaminase by azapurine ribonucleosides
(Elsevier, 1992-11-03)
We have synthesized several 8-azapurine nucleosides as inhibitors of adenosine deaminase. The presence of a nitrogen on the imidazole ring decreased the Ki value for nebularine by 100-fold but did not lower the Ki value ...
CD28 and staphylococcal enterotoxins synergize to induce MHC-independent T-cell proliferation
(Elsevier, 1992-11)
The bacterial exotoxins staphylococcal enterotoxin A and B (SEA and SEB) mediate disease through their effects on T lymphocytes. In this manuscript we have demonstrated that both SEA and SEB can directly activate purified ...
Synthesis of high-affinity, hydrophobic monosaccharide derivatives and study of their interaction with concanavalin A, the pea, the lentil, and fava bean lectins
(Elsevier, 1992-12)
Concanavalin A (Con A) and agglutinins from the pea (PSA), lentil (LCH), and fava bean (VFA) constitute a group of -mannose/-glucose binding legume lectins. In addition to their sugar binding specificity, these lectins ...
Some P---H bond substitution derivatives and fluxionality of Cp2Mo2([mu]-H)([mu]-PHPh)(CO)4
(Elsevier, 1992-11-10)
Reaction of PH2Ph with Cp2Mo2(CO)4 (Mo[triple bond]Mo) results in sequential formation of Cp2Mo2(CO)4(PH2Ph)2 and fluxional Cp2Mo2([mu]-H)([mu]-PHPh)(CO)4. Proton abstraction from Cp2Mo2([mu]-H)([mu]-PHPh)(CO)4 affords ...
Sulfided heterogeneous, bimetallic Ru/Mo catalysts derived from mixtures of Ru 3 (CO) 12 (or RuCl 3 ) and a molybdenum heteropolyanion: The reactions of ethanol with tetrahydroquinoline
(John Wiley & Sons Ltd., 1992-09)
Efforts have been made to develop Ru/Mo bimetallic catalyst systems for hydrodenitrogenation (HDN) of tetrahydroquinoline (THQ). In the course of these studies, it was discovered that in ethanol, under hydrogen and in the ...
Preparation of highly functionalized 3,4-disubstituted cyclobutene-1,2-diones using functionalized zinc-copper organometallics
(Elsevier, 1992)
The selective substitution reactions of the zinc-copper reagents with 3,4-dichlorocyclobutene-1,2-dione 2 allows to prepare a variety of new functionalized symmetrical and mixed 2,4-disubstituted cyclobutene-1,2-diones of ...
Protamine immobilization and heparin adsorption on the protamine-bound cellulose fiber membrane
(Wiley Subscription Services, Inc., A Wiley Company, 1992-02-20)
Immobilization of protamine to the inner lumen of cellulose hollow fibers has been shown useful in preventing both heparin- and protamine-induced complications during an extracorporeal blood circulation procedure. The ...
Irreversible enzyme-shuttle immunoassay
(Wiley Subscription Services, Inc., A Wiley Company, 1992-03-25)
The concept of a competitive enzyme immunoassay that utilizes simultaneously the bound and the free analyte-enzyme conjugate (heterobifunctional conjugate) for signal generation in response to varying analyte concentrations ...
cis-2-Tri-n-butylstannylvinyl cuprates: a new synthon for the cis-1,2-ethene dianion
(Elsevier, 1992-01-01)
Conjugate additions of lower order and higher order cyano cuprates containing the cis-2-tri-n-butylstannylvinyl group to cycloalkenones have been studied. The higher order cuprates were more reactive towards hindered enones ...
Alu-PCR: Characterization of a chromosome 6-specific hybrid mapping panel and cloning of chromosome-specific markers
(Elsevier, 1992-03)
The Alu-polymerase chain reaction (Alu-PCR) was applied to selectively amplify DNA sequences from human chromosome 6 using a single primer (A1) directed to the human Alu consensus sequence. A specific amplification pattern ...