Now showing items 961-970 of 999
Effects of extractive fermentation on butyric acid production by Clostridium acetobutylicum
(Springer-Verlag, 1990-01)
The addition of an oleyl alcohol extractant to a batch fermentation of glucose by Clostridium acetobutylicum resulted in a concentration profile that was distinctly different from the non-extractive control fermentation. ...
Pharmacophore elements of the TIPP class of delta opioid receptor antagonists
(Kluwer Academic Publishers; ESCOM Science Publishers B.V. ; Springer Science+Business Media, 1994-10)
A series of tri-and tetrapeptides sharing the amino-terminal dipeptide unit Tyr-Tic, found in the high-affinity delta opioid receptor antagonist Tyr-Tic-Phe-Phe (TIPP), was prepared and evaluated in receptor binding assays ...
Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat
(Springer-Verlag, 1993-01)
This study examined whether the anticholinergic potency of the clinically superior antipsychotic drug clozapine contributes to clozapine's anatomically-selective functional inhibition of the mesolimbic dopamine (DA) system, ...
Sensitization and tolerance to the discriminative stimulus effects of mu-opioid agonists
(Springer-Verlag, 1994-05)
The discriminative stimulus effects of several μ-opioid agonists were examined under conditions of opioid sensitization or tolerance, i.e., before and after 1-week SC infusions of naloxone or μ-opioid agonists. Rats were ...
Capabilities of two- and three-dimensional FDG-PET for detecting small lesions and lymph nodes in the upper torso: a dynamic phantom study
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1999-01)
The capabilities and limitations of two-(2D) and three-dimensional (3D) fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) in detecting small tumors and lymph nodes were studied in a phantom modeling the ...
Nucleotide Sequence of the 18-kb Conjugative Transposon Tn916 from Enterococcus faecalis
(Elsevier, 1994-11)
Conjugative transposon Tn916 from Enterococcus faecalis DS16 encodes tetracycline resistance (Tet M) as well as determinants necessary for its own movement. Determination of the nucleotide sequence of Tn916 has been ...
Local administration of Δ9-tetrahydrocannabinol attenuates capsaicin-induced thermal nociception in rhesus monkeys: a peripheral cannabinoid action
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1999-04)
Rationale: Cannabinoids can reduce nociceptive responses by acting on peripheral cannabinoid receptors in rodents. Objectives: The study was conducted to evaluate the hypothesis that local administration of Δ 9 ...
VCAM-1 influences Lymphocyte Proliferation and Cytokine Production during Mixed Lymphocyte Responses
(Elsevier, 1994-03)
The allogeneic mixed lymphocyte reaction (MLR) is regarded as an effective model for examining the events which occur during an allospecific immune response. Numerous studies have delineated the role of adherence molecule ...
Tumor-specific granulocyte/macrophage colony-stimulating factor and interferon γ secretion is associated with in vivo therapeutic efficacy of activated tumor-draining lymph node cells
(Springer-Verlag, 1995-09)
In this study, cytokine release by tumor-draining lymph node cells sensitized in vitro (IVS-TDLN) was examined and correlated with therapeutic efficacy in adoptive immunotherapy. Mice bearing immunologically distinct MCA ...
Augmentation of ouabain sensitivity of rat liver Na/K‐ATPase by in vivo adenovirus‐mediated expression of the Na/K‐ATPase α2 subunit
(Wiley Periodicals, Inc., 1997-03-17)