Now showing items 1-10 of 11
Fitting Semiparametric Additive Hazards Models using Standard Statistical Software
(WILEY-VCH Verlag, 2007-10)
The Cox proportional hazards model has become the standard in biomedical studies, particularly for settings in which the estimation covariate effects (as opposed to prediction) is the primary objective. In spite of the ...
Monte Carlo evaluation of object shape effects in iodine-131 SPET tumor activity quantification
(Springer-Verlag, 2001-07)
In our clinical iodine-131 single-photon emission tomography (SPET) quantification for radioimmunotherapy, calibration and partial volume correction are based on measurements with phantoms containing spheres to simulate ...
Analysis of Case-Control Age-at-Onset Data Using a Modified Case-Cohort Method
(WILEY-VCH Verlag, 2008-04)
Case-control designs are widely used in rare disease studies. In a typical case-control study, data are collected from a sample of all available subjects who have experienced a disease (cases) and a sub-sample of subjects ...
A Mixed Model-Based Variance Estimator for Marginal Model Analyses of Cluster Randomized Trials
(WILEY-VCH Verlag, 2007-06)
Generalized estimating equations (GEE) are used in the analysis of cluster randomized trials (CRTs) because: 1) the resulting intervention effect estimate has the desired marginal or population-averaged interpretation, and ...
Scatter modelling and compensation in emission tomography
(Springer-Verlag, 2004-05)
In nuclear medicine, clinical assessment and diagnosis are generally based on qualitative assessment of the distribution pattern of radiotracers used. In addition, emission tomography (SPECT and PET) imaging methods offer ...
A Novel Application of the MIRC Repository in Medical Education
(Springer-Verlag; SCAR (Society for Computer Applications in Radiology), 2005-06)
Medical students on the radiology elective in our institution create electronic presentations to present to each other as part of the requirements for the rotation. Access was given to previous students’ presentations via ...
Clinical role of 99m TcO 4 /MIBI scan, ultrasound and intra-operative gamma probe in the performance of unilateral and minimally invasive surgery in primary hyperparathyroidism
(Springer-Verlag, 2001-09)
The main purposes of this study were: (a) to investigate the efficacy of an imaging protocol based on the combination of 99m TcO 4 /MIBI scintigraphy and neck ultrasound (US) in selecting patients with primary hyperparathyroidism ...
Raman spectral signatures of mouse mammary tissue and associated lymph nodes: normal, tumor and mastitis
(John Wiley & Sons, Ltd., 2007-02)
Raman spectroscopy involves the interaction of light with the molecular vibrations and therefore can provide information about molecular structure, tissue composition and changes in its environment. We explored whether ...
Trends in early mineralization of murine calvarial osteoblastic cultures: a Raman microscopic study
(John Wiley & Sons, Ltd., 2002-07)
The elucidation of early mineralization of bone is of great interest to the medical world. A clearer understanding of the initial bone formation processes can lead to information regarding the treatment and prevention of ...
Intact-protein based sample preparation strategies for proteome analysis in combination with mass spectrometry
(Wiley Subscription Services, Inc., A Wiley Company, 2005-05)
The complexity of tissue and cell proteomes and the vast dynamic range of protein abundance present a formidable challenge for analysis that no one analytical technique can overcome. As a result, there is a need to integrate ...