Now showing items 1-4 of 4
Computational Methods for Understanding Dynamics in Mass Transport and Tissue Development
(2020)
Elucidating the process by which a biological system evolves and properly identifying hidden states and influential underlying factors are important for studying biological functions and origins of diseases. However, due ...
Development and Application of Numerical Methods in Biomolecular Solvation
(2021)
This work addresses the development of fast summation methods for long range particle interactions and their application to problems in biomolecular solvation, which describes the interaction of proteins or other biomolecules ...
Exploring Drug Bioaccumulation and Stabilization with Respect to Endolysosomal Ion Homeostasis Using a Systems-Based Mathematical Modeling Approach
(2018)
Even though most of the FDA approved drugs currently out in the market and in the process of development are weakly basic drugs, the bioaccumulation and stabilization of these drugs are not well understood. For this purpose, ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...