Now showing items 1-10 of 438
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Identification of prognostic factors and risk groups in patients found to have nodal metastasis at the time of radical hysterectomy for early-stage squamous carcinoma of the cervix
(Elsevier, 1989-11)
In a retrospective study conducted at the University of Alabama at Birmingham, the University of Michigan, and the Mayo Clinic, 185 patients with previously untreated FIGO stage IB and IIA squamous cell carcinoma of the ...
Effect of p53 overexpression on radiation sensitivity of human colon cancer cells
(John Wiley & Sons, Inc., 1997)
Substantial controversy surrounds our understanding of the effect of p53 status on radiation sensitivity. To assess directly the role of p53 expression on radiation sensitivity, we chose a conditional expression system ...
Invasive squamous carcinoma of the vulva in young patients
(Elsevier, 1982-04)
Over a 30-year period, 17 patients below the age of 35 with invasive squamous carcinoma of the vulva were identified, 8 of whom (47.1%) had "microinvasive" disease. Venereal diseases and condyloma accuminata were not ...
Imaging Changes after Stereotactic Radiosurgery of Primary and Secondary Malignant Brain Tumors
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-01)
After radiosurgery of malignant tumors, it can be difficult to discriminate between transient treatment effects, radiation necrosis, and tumor progression on post-treatment imaging. Misinterpretation of an enlarging lesion ...
Effect of Neuropeptide Y on Natural Killer Activity of Normal Human Lymphocytes
(Elsevier, 1993-03)
The in vitro effect of neuropeptide Y (NPY) on natural killer (NK) cell activities of normal lymphocytes was investigated. NPY at 10-9 to 10-12M concentrations produced significant suppression of NK activity against K 562 ...
Use of mycophenolate mofetil in steroid-dependent and -resistant nephrotic syndrome
(Springer-Verlag; IPNA, 2003-08)
Cyclosporin (Cs-A) is an effective treatment for difficult cases of nephrotic syndrome (NS), but its use can be complicated by renal toxicity and a high incidence of relapses after withdrawal. We reviewed the charts of 10 ...
Cytogenetic analysis of posterior uveal melanoma
(Elsevier, 1993-03)
Cytogenetic analysis was performed on short-term cultures of primary tumor samples from seven patients with posterior uveal melanoma. Informative data were obtained from four patients, all of whom had a near-diploid ...
Expedition Inspiration Fund for Breast Cancer Research Meeting 2003
(Kluwer Academic Publishers; Springer Science+Business Media, 2003-07)
Clinicopathologic features of ovarian mixed mesodermal tumors and carcinosarcomas
(Elsevier, 1989-02)
Over a 27-year period there were 15 patients treated at the University of Michigan Medical center for carcinosarcomas or mixed mesodermal tumors of the ovary. Overall median survival was 11 months. Median survival was 4 ...