Now showing items 891-900 of 925
Hyporheic Interactions Increase Zinc Exposure and Effects on Hyalella azteca in Sediments under Flow‐Through Conditions
(Academic, San DiegoWiley Periodicals, Inc., 2019-11)
Groundwater–surface water interactions in the hyporheic transition zone can influence contaminant exposure to benthic macroinvertebrates. In streams, hyporheic flows are subject to varying redox conditions, which influence ...
A concept‐wide association study to identify potential risk factors for nonadherence among prevalent users of antihypertensives
(Wiley Periodicals, Inc., 2019-10)
PurposeWe sought to determine whether an association study using information contained in clinical notes could identify known and potentially novel risk factors for nonadherence to antihypertensive medications.MethodsWe ...
Combining sequence data from multiple studies: Impact of analysis strategies on rare variant calling and association results
(Wiley Periodicals, Inc., 2020-01)
Individual sequencing studies often have limited sample sizes and so limited power to detect trait associations with rare variants. A common strategy is to aggregate data from multiple studies. For studying rare variants, ...
Semiclassical transition state theory/master equation kinetics of HO + CO: Performance evaluation
(World ScientificWiley Periodicals, Inc., 2020-12)
Previously, master equation (ME) simulations using semiclassical transition state theory (SCTST) and high‐accuracy extrapolated ab initio thermochemistry (HEAT) predicted rate constants in excellent agreement with published ...
Recent Progress in Steroid Synthesis Triggered by the Emergence of New Catalytic Methods
(Wiley‐VCH, 2020-02-21)
Palmitate‐TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing
(Wiley Periodicals, Inc., 2020-12)
Chronic macrophage inflammation is a hallmark of type 2 diabetes (T2D) and linked to the development of secondary diabetic complications. T2D is characterized by excess concentrations of saturated fatty acids (SFA) that ...
β‐Mannosylation through O‐Alkylation of Anomeric Cesium Alkoxides: Mechanistic Studies and Synthesis of the Hexasaccharide Core of Complex Fucosylated N‐Linked Glycans
(Wiley Periodicals, Inc.CRC Press, 2020-04-23)
Hydrogen Sulfide Oxidation by Sulfide Quinone Oxidoreductase
(Wiley Periodicals, Inc., 2021-03-16)
Hydrogen sulfide (H2S) is an environmental toxin and a heritage of ancient microbial metabolism that has stimulated new interest following its discovery as a neuromodulator. While many physiological responses have been ...
A utility approach to individualized optimal dose selection using biomarkers
(Wiley Periodicals, Inc., 2020-03)
In many settings, including oncology, increasing the dose of treatment results in both increased efficacy and toxicity. With the increasing availability of validated biomarkers and prediction models, there is the potential ...
The role of environmental exposures and the epigenome in health and disease
(John Wiley & Sons, Inc., 2020-01)