Now showing items 911-920 of 925
Timing of androgen deprivation therapy use and fracture risk among elderly men with prostate cancer in the United States
(John Wiley & Sons, Ltd, 2012-01)
Purpose Fractures are a recognized consequence of androgen deprivation therapy (ADT); however, less is known about the incidence of fracture in relation to the timing of ADT use or the impact of fracture on mortality in ...
Nitric Oxide Release for Enhanced Biocompatibility and Analytical Performance of Implantable Electrochemical Sensors
(Wiley Periodicals, Inc.ASM Press, 2021-09)
The real‐time, continuous monitoring of glucose/lactate, blood gases and electrolytes by implantable electrochemical sensors holds significant value for critically ill and diabetic patients. However, the wide‐spread use ...
Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2000-02)
Rationale : By acting on peripheral opioid receptors, opioid agonists can attenuate nociceptive responses induced by a variety of agents. Objectives : This study was conducted to characterize capsaicin-induced thermal ...
Sustainable Green Polymerizations and End-of-Life Treatment of Polymers
(Wiley Periodicals, Inc., 2022-07)
Circuit topology predicts pathogenicity of missense mutations
(John Wiley & Sons, Inc., 2022-09)
The contact topology of a protein determines important aspects of the folding process. The topological measure of contact order has been shown to be predictive of the rate of folding. Circuit topology is emerging as another ...
A Solid Alkylation: Highly Recyclable, Flow Chemistry-Ready, Resin-Supported Thioimidazoliums Alkylate Sulfur-Centered Nucleophiles
(National Institute of Advanced Industrial ScienceWiley Periodicals, Inc., 2022-09-20)
A series of readily regenerable thioimidazolium-based ionic liquids, which can transfer alkyl groups to nucleophiles, are immobilized on crosslinked polystyrene beads. Different alkyl groups can be loaded onto the resin, ...
The Total Synthesis of Glycolipids from Streptococcus pneumoniae and a Re-evaluation of Their Immunological Activity**
(ElsevierWiley Periodicals, Inc., 2022-09-16)
Invariant natural killer (iNK) T cells, Type I iNKTs, are responsible for the production of pro-inflammatory cytokines which induce a systemic immune response. They are distinctive in possessing an semi-invariant T-cell ...
Optimization of RiPCA for the Live-Cell Detection of Pre-MicroRNA-Protein Interactions
(Wiley Periodicals, Inc., 2022-12-16)
Advancements in methods for identifying RNA-protein interactions (RPIs) on a large scale has necessitated the development of assays for validation of these interactions, particularly in living cells. We previously reported ...
Transparent and Self-Healing Elastomers for Reconfigurable 3D Materials
(Wiley Periodicals, Inc., 2022-12)
Transparent soft materials are widely used in applications ranging from packaging to flexible displays, wearable devices, and optical lenses. Nevertheless, soft materials are susceptible to mechanical damage, leading to ...
ER exit sites (ERES) and ER–mitochondria encounter structures (ERMES) often localize proximally
(Wiley Periodicals, Inc., 2023-01)