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Directed biosynthesis of unnatural alkaloids in Dolichothele sphaerica

dc.contributor.authorRosenberg, Harryen_US
dc.contributor.authorStohs, Sidney J.en_US
dc.contributor.authorPaul, Ara G.en_US
dc.date.accessioned2006-04-07T16:47:00Z
dc.date.available2006-04-07T16:47:00Z
dc.date.issued1974-05en_US
dc.identifier.citationRosenberg, Harry, Stohs, Sidney J., Paul, Ara G. (1974/05)."Directed biosynthesis of unnatural alkaloids in Dolichothele sphaerica." Phytochemistry 13(5): 823-828. <http://hdl.handle.net/2027.42/22364>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TH7-42WH5V6-8/2/2900082844362cbd528270faf417953fen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/22364
dc.description.abstractUsing appropriate precursors, the two unnatural alkaloids 4(5)-[N-isocaproylaminomethyl]imidazole and 3-[2-N-isovalerylaminoethyl]pyrazole were produced by Dolichothele sphaerica. The former compound represents an unnatural alkaloid formed by the simultaneous introduction of two unnatural precursors, namely isocaproic acid and 4(5)-aminomethylimidazole. The latter compound represents an aberrant alkaloid formed by the introduction of a precursor of different heterocyclic entity, 3-aminoethylpyrazole.en_US
dc.format.extent425178 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleDirected biosynthesis of unnatural alkaloids in Dolichothele sphaericaen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, MI 48104, U.S.A.en_US
dc.contributor.affiliationotherCollege of Pharmacy, The University of Nebraska, Lincoln, NE 68508, U.S.A.en_US
dc.contributor.affiliationotherCollege of Pharmacy, The University of Nebraska, Lincoln, NE 68508, U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/22364/1/0000811.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0031-9422(00)91146-4en_US
dc.identifier.sourcePhytochemistryen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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