Selective modulation of morphine antinociception, but not development of tolerance, by [delta] receptor agonists
dc.contributor.author | Qi, Jiang | en_US |
dc.contributor.author | Mosberg, Henry I. | en_US |
dc.contributor.author | Porreca, Frank | en_US |
dc.date.accessioned | 2006-04-10T13:36:56Z | |
dc.date.available | 2006-04-10T13:36:56Z | |
dc.date.issued | 1990-09-04 | en_US |
dc.identifier.citation | Qi Jiang, , Mosberg, Henry I., Porreca, Frank (1990/09/04)."Selective modulation of morphine antinociception, but not development of tolerance, by [delta] receptor agonists." European Journal of Pharmacology 186(1): 137-141. <http://hdl.handle.net/2027.42/28392> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T1J-47RWRJK-N/2/c7a2ec66ce661da54b6bde77deb2066a | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/28392 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2178093&dopt=citation | en_US |
dc.description.abstract | Co-administration of [delta] opioid agonists at doses which do not produce measurable antinociception were demonstrated to produce an increase in the antinociceptive potency of morphine in the mouse tail-flick test. In contrast, co-administration of equi-antinociceptive combinations of a [delta] agonist plus morphine for three days resulted in the development of less tolerance to morphine antinociceptive actions. The data indicate that while acute antinociceptive effects of opioid [mu] agonists are modulated by [delta] agonists, the development of antinociceptive tolerance is not. | en_US |
dc.format.extent | 558399 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Selective modulation of morphine antinociception, but not development of tolerance, by [delta] receptor agonists | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Pharmacology, University of Arizona Health Sciences Center, Tucson, AZ 85724, U.S.A. | en_US |
dc.contributor.affiliationother | Department of Pharmacology, University of Arizona Health Sciences Center, Tucson, AZ 85724, U.S.A. | en_US |
dc.identifier.pmid | 2178093 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/28392/1/0000167.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0014-2999(90)94071-5 | en_US |
dc.identifier.source | European Journal of Pharmacology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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