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Design, synthesis and activity against human cytomegalovirus of non-phosphorylatable analogs of toyocamycin, sangivamycin and thiosangivamycin
dc.contributor.authorRenau, Thomas E.en_US
dc.contributor.authorLudwig, Mary S.en_US
dc.contributor.authorDrach, John C.en_US
dc.contributor.authorTownsend, Leroy B.en_US
dc.date.accessioned2006-04-10T14:59:24Z
dc.date.available2006-04-10T14:59:24Z
dc.date.issued1992-12en_US
dc.identifier.citationRenau, Thomas E., Ludwig, Mary S., Drach, John C., Townsend,, Leroy B. (1992/12)."Design, synthesis and activity against human cytomegalovirus of non-phosphorylatable analogs of toyocamycin, sangivamycin and thiosangivamycin." Bioorganic &amp; Medicinal Chemistry Letters 2(12): 1755-1760. <http://hdl.handle.net/2027.42/29717>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TF9-42M846V-8C/2/69cc0e0bd607fafff6f3974050696944en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29717
dc.description.abstractA number of 7-alkyl 4-aminopyrrolo[2,3-pyrimidine derivatives related to toyocamycin, sangivamycin and thiosangivamycin have been prepared and tested for their activity against human cytomegalovirus (HCMV). Only the thioamide substituted derivatives demonstrated biological activity.en_US
dc.format.extent364190 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleDesign, synthesis and activity against human cytomegalovirus of non-phosphorylatable analogs of toyocamycin, sangivamycin and thiosangivamycinen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumInterdepartamental Program in Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109-1065 U.S.A.en_US
dc.contributor.affiliationumDepartment of Biologic and Material Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48109-1065 U.S.A.en_US
dc.contributor.affiliationumDepartment of Biologic and Material Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48109-1065 U.S.A.en_US
dc.contributor.affiliationumDepartment of Chemistry, College of Literature, Arts and Sciences, University of Michigan, Ann Arbor, Michigan 48109-1065 U.S.A.; Interdepartamental Program in Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109-1065 U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29717/1/0000051.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0960-894X(00)80470-9en_US
dc.identifier.sourceBioorganic &amp; Medicinal Chemistry Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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