Phenytoin crystal growth rates in the presence of phosphate and chloride ions
dc.contributor.author | Zipp, Gail L. | en_US |
dc.contributor.author | Rodriguez-Hornedo, Nair | en_US |
dc.date.accessioned | 2006-04-10T15:05:53Z | |
dc.date.available | 2006-04-10T15:05:53Z | |
dc.date.issued | 1992-09 | en_US |
dc.identifier.citation | Zipp, G. L., Rodriguez-Hornedo, N. (1992/09)."Phenytoin crystal growth rates in the presence of phosphate and chloride ions." Journal of Crystal Growth 123(1-2): 247-254. <http://hdl.handle.net/2027.42/29867> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6TJ6-46D6V96-141/2/1bc6c5dd9ab9a32eb365c92705591d08 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/29867 | |
dc.description.abstract | Phenytoin crystal growth kinetics have been measured as a function of supersaturation in pH 2.2 phosphoric acid and pH 2.2 hydrochloric acid solutions. Two different methods were used for the kinetic analysis. The first involved a zone-sensing device which provided an analysis of the distribution of crystals in a batch crystallizer. Crystal growth rates were calculated from the increase in the size of the distribution with time. In the second method, growth rates were evaluated from the change in size with time of individual crystals observed under an inverted microscope. The results from each method compare favorably. The use of both techniques provides an excellent opportunity to exploit the strengths of each: an average growth rate from a population of crystals from batch crystallization and insight into the effect of growth on the morphology of the crystals from the individual crystal measurements. | en_US |
dc.format.extent | 634815 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Phenytoin crystal growth rates in the presence of phosphate and chloride ions | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Physics | en_US |
dc.subject.hlbsecondlevel | Mathematics | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan 48109-1065, USA | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan 48109-1065, USA | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/29867/1/0000215.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0022-0248(92)90030-M | en_US |
dc.identifier.source | Journal of Crystal Growth | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.