View Item 

Show simple item record

Benzimidazole ribonucleosides: Observation of an unexpected nitration when performing non-aqueous diazotizations with t-butyl nitrite
dc.contributor.authorDevivar, Rodrigo V.en_US
dc.contributor.authorDrach, John C.en_US
dc.contributor.authorTownsend, Leroy B.en_US
dc.date.accessioned2006-04-10T15:06:52Z
dc.date.available2006-04-10T15:06:52Z
dc.date.issued1992-09en_US
dc.identifier.citationDevivar, Rodrigo V., Drach, John C., Townsend,, Leroy B. (1992/09)."Benzimidazole ribonucleosides: Observation of an unexpected nitration when performing non-aqueous diazotizations with t-butyl nitrite." Bioorganic &amp; Medicinal Chemistry Letters 2(9): 1105-1110. <http://hdl.handle.net/2027.42/29891>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6TF9-431C6RD-1P/2/cfff140b3097d8a7bff2b6c50c78b193en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/29891
dc.description.abstractMild, non-acidic conditions used in the non-aqueous diazotization of a 2-aminobenzimidazole nucleoside with t-butyl nitrite gave an unexpected 4-nitrobenzimidazol-2-one nucleoside which was not formed when primary alkyl nitrites were used. The isolated compounds were evaluated for activity against herpesviruses and for cytotoxicity against human foreskin fibroblast cells.en_US
dc.format.extent581609 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleBenzimidazole ribonucleosides: Observation of an unexpected nitration when performing non-aqueous diazotizations with t-butyl nitriteen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Medicinal Chemistry, College of Pharmacy, The University of Michigan, Ann Arbor, MI 48109-1065 U.S.A.en_US
dc.contributor.affiliationumDepartment of Biologic and Materials Sciences, School of Dentistry, The University of Michigan, Ann Arbor, MI 48109-1065 U.S.A.en_US
dc.contributor.affiliationumDepartment of Chemistry, College of Literature, Science and Arts, The University of Michigan, Ann Arbor, MI 48109-1065 U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/29891/1/0000244.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0960-894X(00)80628-9en_US
dc.identifier.sourceBioorganic &amp; Medicinal Chemistry Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
0000244.pdf
Size:
567.9KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.