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Model studies of lantibiotic biogenesis

dc.contributor.authorToogood, Peter L.en_US
dc.date.accessioned2006-04-10T15:28:22Z
dc.date.available2006-04-10T15:28:22Z
dc.date.issued1993-12-03en_US
dc.identifier.citationToogood, Peter L. (1993/12/03)."Model studies of lantibiotic biogenesis." Tetrahedron Letters 34(49): 7833-7836. <http://hdl.handle.net/2027.42/30395>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6THS-42H2HRV-H0/2/5681ee614078f30fb9f6ada13c6cbb3cen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/30395
dc.description.abstractA six residue polypeptide has been synthesized to study the proposed biosynthesis of lanthionine. It is shown that this peptide spontaneously cyclizes in a biomimetic fashion via a completely stereoselective intramolecular Michael addition to form (2s, 6R)-lanthionine, as found in naturally occurring lantibiotics.en_US
dc.format.extent257433 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleModel studies of lantibiotic biogenesisen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumWillard H. Dow Laboratories, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109-1055 U.S.A.en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/30395/1/0000014.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/S0040-4039(00)61488-0en_US
dc.identifier.sourceTetrahedron Lettersen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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