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The production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygen

dc.contributor.authorMassey, Vincenten_US
dc.contributor.authorStrickland, S.en_US
dc.contributor.authorMayhew, Stephen G.en_US
dc.contributor.authorHowell, Larry G.en_US
dc.contributor.authorEngel, P. C.en_US
dc.contributor.authorMatthews, Rowena Greenen_US
dc.contributor.authorSchuman, Marilynen_US
dc.contributor.authorSullivan, P. A.en_US
dc.date.accessioned2006-04-17T15:16:37Z
dc.date.available2006-04-17T15:16:37Z
dc.date.issued1969-09-10en_US
dc.identifier.citationMassey, V., Strickland, S., Mayhew, S. G., Howell, L. G., Engel, P. C., Matthews, R. G., Schuman, M., Sullivan, P. A. (1969/09/10)."The production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygen." Biochemical and Biophysical Research Communications 36(6): 891-897. <http://hdl.handle.net/2027.42/32895>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4DX4N64-11S/2/197266be83ace52cda8510a6ab4b0defen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/32895
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=5388670&dopt=citationen_US
dc.description.abstractThe generation of O2-- in the reaction of reduced flavins and several flavoproteins has been shown. This has been demonstrated by the ability to catalyse the aerobic reduction of cytochrome and the inhibition of this reduction by erythrocuprein. In contrast to the results with the intact enzyme, the reduction of cytochrome by deflavoxanthine oxidase is not inhibited by erythrocuprein, indicating that the site of production of O2-- in the native enzyme is flavin, rather than non-heme iron.en_US
dc.format.extent386940 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleThe production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygenen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USAen_US
dc.identifier.pmid5388670en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/32895/1/0000274.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(69)90287-3en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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