Embryonic origin of the caudal mesenteric artery in the mouse
dc.contributor.author | Gest, Thomas R. | en_US |
dc.contributor.author | Carron, Michael A. | en_US |
dc.date.accessioned | 2006-04-19T13:27:00Z | |
dc.date.available | 2006-04-19T13:27:00Z | |
dc.date.issued | 2003-03 | en_US |
dc.identifier.citation | Gest, Thomas R.; Carron, Michael A. (2003)."Embryonic origin of the caudal mesenteric artery in the mouse." The Anatomical Record 271A(1): 192-201. <http://hdl.handle.net/2027.42/34292> | en_US |
dc.identifier.issn | 0003-276X | en_US |
dc.identifier.issn | 1097-0185 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/34292 | |
dc.description.abstract | It is commonly held that the caudal mesenteric artery (CaMA, or inferior mesenteric artery in humans) arises in the same manner as the celiac and cranial mesenteric artery (CrMA, or superior mesenteric artery in humans), i.e., from the remodeling of the vitelline system of arteries that surrounds and supports the yolk sac. Conflicting evidence about the precise manner in which the CaMA arises was presented in studies of the luxate syndrome (Carter: J. Genet. 1954;52:1–35) and sirenomelia (Schreiner and Hoornbeek: J. Morphol. 1973;141:345–358) in the mouse. These studies suggested that the CaMA arises from the remodeling of the medial umbilical arterial roots. Later studies of blood vessel development in the hindlimb of the Dominant hemimelic mouse (Gest: Anat. Rec. 1984;208:296; Anat. Rec. 1987;218:49A; Gest and Roden: Anat. Rec. 1988;220:37–38A) also supported the results of the previous studies. The present investigation tests the hypothesis that the CaMA arises as a result of the regression and remodeling of the medial umbilical arterial roots. Vascular corrosion casts of 9.5-13.5-day-old mouse embryos were observed by scanning electron microscopy (SEM). The results of the present investigation agree with the aforementioned studies. The medial umbilical roots initially conduct the blood to the placenta. On days 10-12 the medial umbilical roots regress and remodel into the CaMA, while the lateral umbilical roots take over the blood supply to the placenta. On the basis of our results, we conclude that the CaMA arises from the medial umbilical roots and not from the remodeling of the vitelline system of arteries, as previously assumed. Anat Rec Part A 271A:192–201, 2003. © 2003 Wiley-Liss, Inc. | en_US |
dc.format.extent | 714395 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cell & Developmental Biology | en_US |
dc.title | Embryonic origin of the caudal mesenteric artery in the mouse | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Anatomical Sciences, University of Michigan Medical School, Ann Arbor, Michigan ; Fax: (734) 615-8191 ; Division of Anatomical Sciences, Office of Medical Education, University of Michigan Medical School, Ann Arbor, MI 48109-0608 | en_US |
dc.contributor.affiliationum | University of Michigan Medical School, Ann Arbor, Michigan | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/34292/1/10022_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/ar.a.10022 | en_US |
dc.identifier.source | The Anatomical Record | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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