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Human Intestinal Permeability of Piroxicam, Propranolol, Phenylalanine, and PEG 400 Determined by Jejunal Perfusion

dc.contributor.authorLennernäs, Hansen_US
dc.contributor.authorShah, Vinod P.en_US
dc.contributor.authorBarnett, Jeffrey L.en_US
dc.contributor.authorLesko, Lawrence J.en_US
dc.contributor.authorRhie, Julie K.en_US
dc.contributor.authorWelage, Lynda S.en_US
dc.contributor.authorHayashi, Yayoien_US
dc.contributor.authorTakamatsu, Narushien_US
dc.contributor.authorIdkaidek, Nasir M.en_US
dc.contributor.authorLee, Peter I-Deren_US
dc.contributor.authorLiu, Dong-Yueen_US
dc.contributor.authorAmidon, Gordon L.en_US
dc.date.accessioned2006-09-08T19:16:56Z
dc.date.available2006-09-08T19:16:56Z
dc.date.issued1997-09en_US
dc.identifier.citationTakamatsu, Narushi; Welage, Lynda S.; Idkaidek, Nasir M.; Liu, Dong-Yue; Lee, Peter I-Der; Hayashi, Yayoi; Rhie, Julie K.; Lennernäs, Hans; Barnett, Jeffrey L.; Shah, Vinod P.; Lesko, Lawrence; Amidon, Gordon L.; (1997). "Human Intestinal Permeability of Piroxicam, Propranolol, Phenylalanine, and PEG 400 Determined by Jejunal Perfusion." Pharmaceutical Research 14(9): 1127-1132. <http://hdl.handle.net/2027.42/41460>en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.issn0724-8741en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41460
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9327437&dopt=citationen_US
dc.description.abstractPurpose . To determine the human jejunal permeabilities of compounds utilizing different transport mechanisms using a regional perfusion approach and to establish a standard procedure for determining drug permeability class to be used for the establishment of drug product bioequivalence standards.en_US
dc.format.extent561206 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherPiroxicamen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherMedical Lawen_US
dc.subject.otherIntestinal Permeabilityen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherBiopharmaceutic Classification Schemeen_US
dc.subject.otherDrug Absorptionen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherPharmacyen_US
dc.subject.otherPropranololen_US
dc.titleHuman Intestinal Permeability of Piroxicam, Propranolol, Phenylalanine, and PEG 400 Determined by Jejunal Perfusionen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDepartment of Internal Medicine, Division of Gastroenterology University of Michigan Medical Center, Ann Arbor, Michiganen_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michiganen_US
dc.contributor.affiliationotherSchool of Pharmacy, Uppsala University, Uppsala, Swedenen_US
dc.contributor.affiliationotherFDA/CBER, 1401 Rockville Pike (HFM-515), Rockville, Maryland, 20852-1448en_US
dc.contributor.affiliationotherNagoya City University, Nagoya, Japanen_US
dc.contributor.affiliationotherFood and Drug Administration, Rockville, Maryland, 20857en_US
dc.contributor.affiliationotherJanssen Research Foundation, Titusville, New Jerseyen_US
dc.contributor.affiliationotherFaculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordanen_US
dc.contributor.affiliationotherBiopharmaceutical Computing Center, Beijing Medical University, Beijing, Chinaen_US
dc.contributor.affiliationotherFood and Drug Administration, Rockville, Maryland, 20857en_US
dc.contributor.affiliationotherYamanouchi Pharmaceutical Co. Ltd., Shizuoka, Japanen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid9327437en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41460/1/11095_2004_Article_304276.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1012134219095en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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