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Beta Cyclodextrins Enhance Adenoviral-Mediated Gene Delivery to the Intestine

dc.contributor.authorRoessler, Blake J.en_US
dc.contributor.authorAmidon, Gordon L.en_US
dc.contributor.authorCroyle, Maria A.en_US
dc.contributor.authorSun, Rongen_US
dc.contributor.authorHsu, Cheng-Pangen_US
dc.date.accessioned2006-09-08T19:17:32Z
dc.date.available2006-09-08T19:17:32Z
dc.date.issued1998-09en_US
dc.identifier.citationCroyle, Maria A.; Roessler, Blake J.; Hsu, Cheng-Pang; Sun, Rong; Amidon, Gordon L.; (1998). "Beta Cyclodextrins Enhance Adenoviral-Mediated Gene Delivery to the Intestine." Pharmaceutical Research 15(9): 1348-1355. <http://hdl.handle.net/2027.42/41469>en_US
dc.identifier.issn0724-8741en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41469
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9755884&dopt=citationen_US
dc.description.abstractPurpose . In general, the intestinal epithelium is quite refractory to viral and non-viral methods of gene transfer. In this report, various cyclodextrin formulations were tested for their ability to enhance adenoviral transduction efficiency in two models of the intestinal epithelium: differentiated Caco-2 cells and rat jejunum.en_US
dc.format.extent701884 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherGene Therapyen_US
dc.subject.otherPharmacyen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherCyclodextrinsen_US
dc.subject.otherMedical Lawen_US
dc.subject.otherJejunumen_US
dc.subject.otherAdenovirusen_US
dc.subject.otherIntestineen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.titleBeta Cyclodextrins Enhance Adenoviral-Mediated Gene Delivery to the Intestineen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065; Institute of Human Gene Therapy, Department of Molecular and Cellular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, 19104en_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationumDepartment of Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, Michigan, 48109; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid9755884en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41469/1/11095_2004_Article_303985.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1011985101580en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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