Beta Cyclodextrins Enhance Adenoviral-Mediated Gene Delivery to the Intestine
dc.contributor.author | Roessler, Blake J. | en_US |
dc.contributor.author | Amidon, Gordon L. | en_US |
dc.contributor.author | Croyle, Maria A. | en_US |
dc.contributor.author | Sun, Rong | en_US |
dc.contributor.author | Hsu, Cheng-Pang | en_US |
dc.date.accessioned | 2006-09-08T19:17:32Z | |
dc.date.available | 2006-09-08T19:17:32Z | |
dc.date.issued | 1998-09 | en_US |
dc.identifier.citation | Croyle, Maria A.; Roessler, Blake J.; Hsu, Cheng-Pang; Sun, Rong; Amidon, Gordon L.; (1998). "Beta Cyclodextrins Enhance Adenoviral-Mediated Gene Delivery to the Intestine." Pharmaceutical Research 15(9): 1348-1355. <http://hdl.handle.net/2027.42/41469> | en_US |
dc.identifier.issn | 0724-8741 | en_US |
dc.identifier.issn | 1573-904X | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41469 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9755884&dopt=citation | en_US |
dc.description.abstract | Purpose . In general, the intestinal epithelium is quite refractory to viral and non-viral methods of gene transfer. In this report, various cyclodextrin formulations were tested for their ability to enhance adenoviral transduction efficiency in two models of the intestinal epithelium: differentiated Caco-2 cells and rat jejunum. | en_US |
dc.format.extent | 701884 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Gene Therapy | en_US |
dc.subject.other | Pharmacy | en_US |
dc.subject.other | Biomedical Engineering | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Cyclodextrins | en_US |
dc.subject.other | Medical Law | en_US |
dc.subject.other | Jejunum | en_US |
dc.subject.other | Adenovirus | en_US |
dc.subject.other | Intestine | en_US |
dc.subject.other | Pharmacology/Toxicology | en_US |
dc.title | Beta Cyclodextrins Enhance Adenoviral-Mediated Gene Delivery to the Intestine | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065; Institute of Human Gene Therapy, Department of Molecular and Cellular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, 19104 | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065 | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065 | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, Michigan, 48109; Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, 48109 | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065 | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 9755884 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41469/1/11095_2004_Article_303985.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1023/A:1011985101580 | en_US |
dc.identifier.source | Pharmaceutical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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