Overexpression of Human Intestinal Oligopeptide Transporter in Mammalian Cells via Adenoviral Transduction
dc.contributor.author | Hsu, Cheng-Pang | en_US |
dc.contributor.author | Roessler, Blake J. | en_US |
dc.contributor.author | Hilfinger, John M. | en_US |
dc.contributor.author | Walter, Elke | en_US |
dc.contributor.author | Merkle, Hans P. | en_US |
dc.contributor.author | Amidon, Gordon L. | en_US |
dc.date.accessioned | 2006-09-08T19:17:36Z | |
dc.date.available | 2006-09-08T19:17:36Z | |
dc.date.issued | 1998-09 | en_US |
dc.identifier.citation | Hsu, Cheng-Pang; Hilfinger, John M.; Walter, Elke; Merkle, Hans P.; Roessler, Blake J.; Amidon, Gordon L.; (1998). "Overexpression of Human Intestinal Oligopeptide Transporter in Mammalian Cells via Adenoviral Transduction." Pharmaceutical Research 15(9): 1376-1381. <http://hdl.handle.net/2027.42/41470> | en_US |
dc.identifier.issn | 0724-8741 | en_US |
dc.identifier.issn | 1573-904X | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41470 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9755888&dopt=citation | en_US |
dc.description.abstract | Purpose . Our goals are to establish an in vitro screening system and to evaluate a new approach in improving oral absorption of peptides and peptide-like drugs by overexpression of the human intestinal oligo-peptide transporter (hPepTl). This study characterizes the expression of hPepTl in human intestinal Caco-2 cells, rat intestinal epithelial cells (IEC-18), and human cervix epithelial cells (Hela) after adenoviral transduction. | en_US |
dc.format.extent | 582908 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Biomedical Engineering | en_US |
dc.subject.other | HPepTl | en_US |
dc.subject.other | Pharmacology/Toxicology | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Pharmacy | en_US |
dc.subject.other | Caco-2 Cells | en_US |
dc.subject.other | Drug Screening | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Medical Law | en_US |
dc.subject.other | Gene Expression | en_US |
dc.subject.other | Adenovirus | en_US |
dc.title | Overexpression of Human Intestinal Oligopeptide Transporter in Mammalian Cells via Adenoviral Transduction | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065 | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, Michigan, 48109 | en_US |
dc.contributor.affiliationum | College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065 | en_US |
dc.contributor.affiliationother | Department of Pharmacy, ETH Zurich, CH-8057, Zurich, Switzerland | en_US |
dc.contributor.affiliationother | Department of Pharmacy, ETH Zurich, CH-8057, Zurich, Switzerland | en_US |
dc.contributor.affiliationother | TSRL, Incorporated, Ann Arbor, Michigan, 48108 | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 9755888 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41470/1/11095_2004_Article_303989.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1023/A:1011993303397 | en_US |
dc.identifier.source | Pharmaceutical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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