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Cellular Uptake Mechanism of Amino Acid Ester Prodrugs in Caco-2/hPEPT1 Cells Overexpressing a Human Peptide Transporter
dc.contributor.authorOh, Doo-Manen_US
dc.contributor.authorAmidon, Gordon L.en_US
dc.contributor.authorHan, Hyo-kyungen_US
dc.date.accessioned2006-09-08T19:17:40Z
dc.date.available2006-09-08T19:17:40Z
dc.date.issued1998-09en_US
dc.identifier.citationHan, Hyo-kyung; Oh, Doo-Man; Amidon, Gordon L.; (1998). "Cellular Uptake Mechanism of Amino Acid Ester Prodrugs in Caco-2/hPEPT1 Cells Overexpressing a Human Peptide Transporter." Pharmaceutical Research 15(9): 1382-1386. <http://hdl.handle.net/2027.42/41471>en_US
dc.identifier.issn0724-8741en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41471
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9755889&dopt=citationen_US
dc.description.abstractPurpose . This study characterized the cellular uptake mechanism and hydrolysis of the amino acid ester prodrugs of nucleoside antiviral drugs in the transiently transfected Caco-2 cells overexpressing a human intestinal peptide transporter, hPEPTl (Caco-2/hPEPTl cells).en_US
dc.format.extent467230 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherPharmacyen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherProdrugsen_US
dc.subject.otherAmino Acid Esteren_US
dc.subject.otherBiomedicineen_US
dc.subject.otherMedical Lawen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherCaco-2 Cellsen_US
dc.subject.otherPeptide Transporteren_US
dc.subject.otherPermeabilityen_US
dc.subject.otherCellular Uptakeen_US
dc.titleCellular Uptake Mechanism of Amino Acid Ester Prodrugs in Caco-2/hPEPT1 Cells Overexpressing a Human Peptide Transporteren_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid9755889en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41471/1/11095_2004_Article_303990.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1011945420235en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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